Revista española de anestesiología y reanimación
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Rev Esp Anestesiol Reanim · Oct 1995
Randomized Controlled Trial Clinical Trial[Effect of controlled hypotension using sodium nitroprusside on platelet aggregation].
To determine the influence of sodium nitroprusside (SNP) on platelet aggregation when this agent is used to induce hypotension during surgery. ⋯ Platelet aggregation increases during surgery and in the immediate postoperative period. This increase is attenuated when SPA is given to induce hypotension. SPA should be determined by measurement of impedance in whole blood when the nature of platelet aggregation during surgery is being studied, given that early increases in IPA can be masked as a result of the low sensitivity of turbidimetry.