Journal of the Medical Association of Thailand = Chotmaihet thangphaet
-
Colorectal cancer is the third most common cancer worldwide. There were only a few reports of disease outcomes in Thai. Therefore, the authors retrospectively reviewed the clinical characteristics and disease outcome of patients with curable colorectal cancer treated at Siriraj Hospital, the largest tertiary-care hospital in Thailand. ⋯ Approximately two-thirds (68%) of patients with colorectal cancer at Siriraj hospital presented with a potentially curable stage. Multi-modality treatments with surgery, adjuvant chemotherapy and radiation resulted in comparable survival as in Western countries. Independent risk factors for worse survival in this cohort were stage III disease and male gender.
-
Gabapentin has an antipruritus effect, which its efficacy in reducing pruritus induced by intrathecal morphine has not been well documented. The purpose of the present study was to know if a single smaller dose of gabapentin could decrease the intrathecal morphine-induced pruritus. ⋯ Preoperative gabapentin 600 mg did not significantly reduce the postoperative intrathecal morphine-induced pruritus.
-
Randomized Controlled Trial
Efficacy and hemodynamic outcome of prolonged intermittent renal replacement therapy (PIRRT) in critically ill patients: a preliminary report.
Acute kidney injury (AKI) is frequently part of a multiple-organ dysfunction syndrome presenting in critically ill patients. Prolonged intermittent renal replacement therapy (PIRRT) provides the advantages of both continuous renal replacement therapy (CRRT) in term of hemodynamic stability and the cost-effectiveness of intermittent hemodialysis (IHD). This study aims to study PIRRT in the aspects of efficacy and hemodynamic outcomes. ⋯ The prolonged intermittent renal replacement therapy (PIRRT) appears to be an outstanding technique for treatment of critically ill patients with AKI and it also seems to have cost effectiveness. Moreover it is suitable to a limited resource region such as Thailand.
-
Randomized Controlled Trial
Snake scope camera assisted endotracheal intubation: a procedural skills training in cadaver to prepare preclinical students for their clerkships.
Preparing students to perform specific procedures on patients presents a challenge of student confidence in performing these tasks. This descriptive study determined the ability of the medical students to perform a basic clinical task after a short hands-on training workshop in cadavers. This basic procedural skills training was an attempt for developing conceptual understanding and increasing procedural skills in endotracheal intubation of the medical students. ⋯ The medical students have the ability to accomplish a basic clinical task after a short hands-on training workshop.
-
Nosocomial pneumonia (NP) is an important cause of morbidity and mortality in hospitalized patients. Acinetobacter baumannii is one of the common causative pathogens in NP. The prevalence of multi-drug resistance in A. baumannii has been increasing. The information on clinical features and clinical courses of A. baumannii NP in Thai patients are limited. ⋯ A. baumannii is the most common causative pathogen for NP in tertiary care hospitals in Thailand and most of A. baumannii isolates were resistant to many antibiotics including carbapenems. The hospitalized patient in tertiary care hospitals with VAP, or NP that was developed in medical ICU, or NP with bilateral lung involvements on chest x-ray was likely to be due to A. baumannii. Many NP patients received inappropriate initial antibiotic regimens leading to a high mortality.