Journal of the Indian Medical Association
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Clinical Trial
Sublingual nifedipine in hypertensive emergencies with special reference to cerebrovascular accident.
Effect of sublingual nifedipine was evaluated in 39 cases of hypertensive emergencies (diastolic blood pressure greater than or equal to 120 mm Hg with impending organ failure, loss of vital function or death). It was found to be effective (95%), safe, with prompt (with 15 minutes) and predictable response (lowering of systolic blood pressure, diastolic blood pressure, mean arterial pressure by 30% at the end of 3 hours), and few adverse effects. Its use in patients of cerebrovascular accident (24 cases) was found to be effective and safe without any significant clinical problem or increased mortality.
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Forty cases of diaphyseal fracture of humerus were treated by functional cast bracing (FCB). Results were compared with a series of 25 patients treated by U cast method. Average time taken for union was 7.5 weeks with a range of 5-14 weeks by FCB method. ⋯ More than 50% patients had varus angulation less than 5 degrees after treatment by FCB. Only 16% had varus angulation less than 5 degrees by U cast method while 32% had varus angulation more than 15 degrees. FCB is distinctly superior method of treatment for diaphyseal fracture of humerus.