Anesteziologiia i reanimatologiia
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Anesteziol Reanimatol · Jan 2010
Clinical Trial[Pre-emptive analgesia in the complex of multicomponent general anesthesia in pediatric neurosurgery].
The study enrolled 30 patients aged 2 to 18 years, who had been operated on at the Prof A. L. ⋯ The patients had undergone total intravenous anesthesia with the opioid analgesic fentanyl (3.5 microg/kg x hr), the central alpha 2-adrenoblocker clofelin (1.2 microg/kg x hr), recofol (3 mg/kg x hr) under myorelaxation (arduan, esmeron) and artificial ventilation. Assessment of a neuroendocrine response and postoperative analgesia levels by the physiological and self-appraisal scales showed the high efficacy of pre-emptive analgesia using paracetamol in the complex of multicomponent anesthesia using the central alpha 2-adrenoblocker clofelin.
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Anesteziol Reanimatol · Jan 2010
Clinical Trial[Comparative characteristics of hydroxyzine (atarax) and diazepam in the premedication regimen in children in dental practice].
The effects of hydroxyzine, 2 mg/kg, versus diazepam, 0.5 mg/kg, given orally, on hemodynamics, respiration, and sedative background were studied. The anxiolytic effect of hydroxyzine was higher than that of diazepam. Hydroxyzine showed a minimum effect on hemodynamic and respiratory parameters in children in dental practice before oral sanitation using general anesthesia.
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Anesteziol Reanimatol · Jan 2010
[Experience with sevofluorane and halothane used during general anesthesia in children].
The investigators made a prospective analysis of the specific features of anesthesias with sevoflurane and halothane in 70 children aged 1 to 11 years with systemic surgical diseases and assessed their physical status as ASA Class I. The anesthetics sevoflurane, 3.1 +/- 0.7 MAC, and halothane, 2.4 +/- 0.3 MAC, were used to induce anesthesia. Sevoflurane, 1.6 +/- 0.6 MAC, and halothane, 1.5 +/- 0.4 MAC, were employed to maintain anesthesia. ⋯ The level of blood oxygenation was stable (SpO2 97-99%) in both groups during all observational stages. No severe complications were recorded in both groups during anesthesia. However, mild or moderate complications were twice fewer in the sevoflurane group.