Anesteziologiia i reanimatologiia
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Anesteziol Reanimatol · Jan 2005
Comparative Study Clinical Trial[Comparative assessment of rocuronium bromide and cysatracurium besylate used during endosurgical operations in children].
The authors have studied the effects of the muscular relaxants rocuronium bromide and cysatracurium besylate on neuromuscular conduction, respiration mechanics, and hemodynamics in 120 children during endosurgical operations. The paper comparatively assesses the muscular relaxants and the procedures of their use, which made it possible to ensure controlled and deep relaxation.
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Anesteziol Reanimatol · Jan 2005
Comparative Study[Comparative evaluation of different infusion medias used in therapy for neonatal hypovolemia].
The paper comparatively evaluates the efficiency of the use of physiological sodium chloride solution, freshly-frozen plasma, 6% and 10% solutions of hydroxyethyl starch to compensate for circulating blood volume deficit in 80 neonatal infants aged 1-3 days who had hypovolemia resulting from hemorrhage during labor or abdominal delivery. 6% and 10% solutions of hydroxyethyl starch were found to be the most effective agents for compensating for circulating plasma volume deficit. They rapidly eliminate circulating blood volume deficit, long maintain the stability of systemic and peripheral hemodynamic parameters.
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Anesteziol Reanimatol · Jan 2005
[Central hemodynamic changes in children reoperated on for congenital spinal cord hernia using balanced anesthesia based on midasolam and propofol].
The central hemodynamics was studied and analyzed in 51 patients reoperated on for congenital spinal cord hernia under balanced anesthesia based on midasolam and proforol. The procedure for anesthesiological provision of replastic repair of operated spinal hernia, which is based on propofol of bolus administration of midasolam with a hypnotic appliance, was found to cause no negative hemodynamic effects. When the benzodiazepine antagonist flumazenyl is used, the interval between the end of surgery and tracheal extubation is virtually identical in the propofol and midasolam groups since the intravenous injection of flumazenyl induces a drastic awakening effect.
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Anesteziol Reanimatol · Jan 2005
[Combined spinal epidural anesthesia during endoprosthetic surgeries for bone tumors in old-age children].
Thirty-five patients (ASA II-III) aged 12 to 17 years, diagnosed as having osteogenic sarcoma and Ewing's sarcoma localizing in the femur and tibia, were examined. Surgery was performed as sectoral resection of the affected bone along with knee joint endoprosthesis. Surgical intervention was made under combined spinal and epidural anesthesia (CSEA) with sedation, by using the methods for exact dosing of propofol (6-4 mg/kg x h). ⋯ The acid-alkali balance suggested the adequacy of spontaneous respiration. The only significant complication we observed was atony of the bladder that requires its catheterization till the following day. An epidural catheter makes it possible to effect adequate postoperative analgesia.
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Anesteziol Reanimatol · Jan 2005
[Optimization of antibacterial therapy in operated neonates on the basis of early diagnosis of septic complications].
The paper is based on the results obtained during examination and intensive care in 175 neonatal infants operated on for various malformations who were treated in the pediatric intensive care unit, Moscow Regional Research Institute of Clinical Studies, in 1998 to 2000. Analyzing the results has indicated that 24% of the patients have signs of early sepsis just within the first 24 postoperative hours. ⋯ The studies performed lead to the conclusion that procalcitonin is a highly sensitive and specific marker of sepsis by which postoperative septic complications can be diagnosed in the early periods. The early diagnosis of sepsis, by using the marker procalcitonin permitted timely rational correction of antibiotic therapy, which improved the basic parameters of treatment and reduced deaths from septic complications from 48 to 36%.