Anesteziologiia i reanimatologiia
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Anesteziol Reanimatol · Nov 2013
Clinical Trial[Association of cardiovascular system and endothelial dysfunction indicators in patients with hemorrhagic shock].
Endothelial dysfunction is a universal mechanism of pathogenesis of many critical conditions. Goal of the study was to assess a relation of cardiovascular system and endothelial dysfunction indicators in patients with hemorrhagic shock. ⋯ Performed correlation analysis showed statistically significant relations of cardiovascular system and endothelial dysfunction indicators in patients with hemorrhagic shock. Endothelial dysfunction occurs in patients with hemorrhagic shock 3. The endothelial dysfunction correlates with parameters of cardio-vascular system and tissue perfusion.
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Anesteziol Reanimatol · Nov 2013
Observational Study[Comparison of epidural and opioid analgesia effects on frequency of paralytic ileus development in patients of surgical intensive care unit].
The impact of epidural analgesia (EA) on bowel peristalsis in Surgical Intensive Care Unit (SICU) patients is not well known. This study was designed to determine if EA improves bowel motility and decreases the incidence of postoperative paralytic ileus compared to patients receiving systemic opioid analgesia (OA). Through prospective cohort study we investigated 386 SICU patients who received EA [n = 70 (18.13%)], or OA +/- ketorolac trometamol [n = 316 (81.87%)]. We showed that EA does not improve time to defecation and does not decrease the incidence of paralytic ileus in SICU patients.
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Anesteziol Reanimatol · Nov 2013
[Effect of anaesthesia on incidence of postoperative delirium after major abdominal surgery in elderly patients].
Delirium can be caused by haemodynamics abnormalities during anaesthesia. The main role in delirium appearance is given to decreasing of cerebral perfusion pressure. Especially it can happen in patients with underlying intracranial hypertension. ⋯ The frequency of delirium was higher in patients who had got anaesthesia based on sevoflurane. Additionally these patients had higher frequency of cerebral perfusion pressure decreasing. Conclusions; Anaesthesia based on sevoflurane is characterized by higher frequency of postoperative delirium in elderly patients after major abdominal surgery.
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Anesteziol Reanimatol · Sep 2013
Clinical Trial[Etiopathogenetic extracorporeal treatment of severe sepsis in patients after cardiac surgery].
The study deals with assessment of LPS-adsorption and haemodialysis with EMiC2-filters use in the complex treatment in cardio-surgery patients with heavy sepsis. 64 adult patients included in the study were divided into two groups. 26 patients of the main group with heavy sepsis (EEA > 0.6; procalcitonin level higher than 2 ng/ml) received LPS-adsorption and haemodialysis with EMiC2-filters. 38 patients of control group with heavy sepsis developed after surgeries on heart and vessels did not receive extracorporeal methods of treatment. Positive effect of combined extracorporeal treatment on haemodynamics, oxygenation, endotoxin activity decreasing, procalcitonin level, inflammatory and antiphlogistic cytokines level was identified Trend of 28-day survival increasing was indentified in the main group.