Brazilian journal of anesthesiology (Elsevier)
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Randomized Controlled Trial Comparative Study
Comparison of the effects and complications of unilateral spinal anesthesia versus standard spinal anesthesia in lower-limb orthopedic surgery.
A restricted sympathetic block during spinal anesthesia may minimize hemodynamic changes. This prospective randomized study compared unilateral and bilateral spinal anesthesia with respect to the intra- and postoperative advantages and complications of each technique. ⋯ When unilateral spinal anesthesia was performed using a low-dose, low-volume and low-flow injection technique, it provides adequate sensory-motor block and helps to achieve stable hemodynamic parameters during orthopedic surgery on a lower limb. Patients were more satisfied with this technique as opposed to the conventional approach. Furthermore, this technique avoids unnecessary paralysis on the non-operated side.
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Randomized Controlled Trial
Ondansetron reducing pain on injection of etomidate: a controlled randomized study.
Etomidate causes pain when injected intravenously. In this study we sought to determine if pretreatment by ondansetron reduces the pain on injection of etomidate. ⋯ This study illustrates that pre-treatment with intravenous ondansetron significantly reduces the pain on injection of etomidate.
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Randomized Controlled Trial
Oxygen concentrators performance with nitrous oxide at 50:50 volume.
Few investigations have addressed the safety of oxygen from concentrators for use in anesthesia in association with nitrous oxide. This study evaluated the percent of oxygen from a concentrator in association with nitrous oxide in a semi-closed rebreathing circuit. ⋯ The FiO2 in the mixture of O293 and nitrous oxide fell during the observation period although oxygen saturation was higher than 98.5% throughout the study. Concentrators can be considered a stable source of oxygen for use during short anesthetic procedures, either pure or in association with nitrous oxide at 50:50 volume.
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Comparative Study
Comparison of the effects of dexmedetomidine administered at two different times on renal ischemia/reperfusion injury in rats.
We investigated the effect of dexmedetomidine on ischemic renal failure in rats. ⋯ The results were shown that administration of dexmedetomidine reduced the renal IR injury histomorphologically. Administration of dexmedetomidine in the reperfusion period was considered as more effective due to increase in urinary output and decrease in BUN levels.