World journal of gastroenterology : WJG
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World J. Gastroenterol. · Jul 2013
Clinical significance of melatonin concentrations in predicting the severity of acute pancreatitis.
To assess the value of plasma melatonin in predicting acute pancreatitis when combined with the acute physiology and chronic health evaluation II (APACHEII) and bedside index for severity in acute pancreatitis (BISAP) scoring systems. ⋯ The melatonin concentration is closely related to the severity of AP and the BISAP score. Therefore, we can evaluate the severity of disease by measuring the levels of serum melatonin.
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World J. Gastroenterol. · Jul 2013
Polydatin attenuated food allergy via store-operated calcium channels in mast cell.
To investigate the effect of polydatin (PD), a resveratrol glucoside, on mast cell degranulation and anti-allergic activity. ⋯ Taken together, our data indicate that PD stabilizes mast cells by suppressing intracellular Ca(2+) mobilization, mainly through inhibiting Ca(2+) entry via SOCs, thus exerting a protective role against OVA-sensitized food allergy.