World journal of gastroenterology : WJG
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World J. Gastroenterol. · Mar 2013
Scolopendra subspinipes mutilans protected the cerulein-induced acute pancreatitis by inhibiting high-mobility group box protein-1.
To evaluate the inhibitory effects of Scolopendra subspinipes mutilans (SSM) on cerulein-induced acute pancreatitis (AP) in a mouse model. ⋯ These results suggest that SSM plays a protective role during the development of AP and pancreatitis associated lung injury via deactivating c-Jun NH2-terminal kinase, p38 and NF-κB.
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World J. Gastroenterol. · Mar 2013
Review Meta AnalysisEndoscopic and surgical resection of T1a/T1b esophageal neoplasms: a systematic review.
To investigate potential therapeutic recommendations for endoscopic and surgical resection of T1a/T1b esophageal neoplasms. ⋯ Local tumor recurrence is predicted by grade 3, metachronous cancer by the carcinoma in-situ component, and lymph node positivity by L+. T1b cancer should be treated with surgical resection.
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World J. Gastroenterol. · Mar 2013
Comparative StudyMiddle segmental pancreatectomy: a safe and organ-preserving option for benign and low-grade malignant lesions.
To study the feasibility and safety of middle segmental pancreatectomy (MSP) compared with pancreaticoduodenectomy (PD) and extended distal pancreatectomy (EDP). ⋯ MSP is a safe and organ-preserving option for benign or low-grade malignant lesions in the neck and proximal body of the pancreas.
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World J. Gastroenterol. · Mar 2013
Decision making for pancreatic resection in patients with intraductal papillary mucinous neoplasms.
To identify a practical approach for preoperative decision-making in patients with intraductal papillary mucinous neoplasms (IPMNs) of the pancreas. ⋯ Combining preoperative CT/MRI images and CA19-9 level may provide useful information for surgical decision-making in IPMNs.
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Early identification of acute mesenteric ischemia (AMI) is challenging. The wide variability in clinical presentation challenges providers to make an early accurate diagnosis. Despite major diagnostic and treatment advances over the past decades, mortality remains high. ⋯ Thus, AMI could be diagnosed earlier with follow-up computed tomographic angiography or high spatial magnetic resonance imaging. Experimental in vitro and in vivo studies show promise for alpha glutathione S transferase and intestinal fatty acid binding protein as markers for AMI. Future research must confirm the clinical utility of these biochemical markers in the diagnosis of mesenteric ischemia.