Postgraduate medicine
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Postgraduate medicine · May 2022
Observational StudyClinical spectrum of immunoglobulin A vasculitis in children and determining the best timing of urine examination to predict renal involvement.
Immunoglobulin A (IgA) vasculitis (also known as Henoch-Schonlein purpura) is the most common small vessel vasculitis of childhood. The long-term prognosis depends on renal involvement. The aim of this study was to evaluate the risk factors associated with renal involvement in children with IgA vasculitis and to investigate the best timing of urine examination to predict the presence of renal involvement at the sixth month after the diagnosis. ⋯ This study has demonstrated that the optimal date to predict the presence of hematuria and/or proteinuria in the sixth month is the urine examination performed in the first month of the disease. Therefore, we think that patients with IgA vasculitis who show a presence of hematuria and/or proteinuria in the first-month urine examination should be followed more closely.
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Postgraduate medicine · May 2022
Adjuvant radiotherapy did not increase the risk of coronary heart disease in patients with non-metastatic breast cancer.
Adjuvant radiotherapy (RT) in patients with breast cancer can adversely cause the heart to receive some radiation doses, which may lead to cardiovascular diseases. The results of previous research regarding this issue are not consistent. Therefore, we conducted a nationwide population-based study in Taiwan to evaluate whether adjuvant RT for breast cancer patients increased the risk of developing coronary heart disease (CHD). ⋯ This large, nationwide cohort study suggests that adjuvant RT in patients with breast cancer did not increase the risk of CHD.