Postgraduate medicine
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Postgraduate medicine · Aug 2021
A Gastroenterologist' clinical experience in COVID 19 and in-hospital mortality and length of stay analysis.
COVID19 pandemic has forced physicians from different specialties to assist cases overload. Our aim is to assess gastroenterologist's assistance in COVID-19 by assessing mortality, ICU admission, and length of stay, and seek for risk factors for in-hospital mortality and longer hospital stay. ⋯ COVID-19 assistance was similar between gastroenterologist and COVID experts when assessing mortality, ICU admission, and length of stay. Age>70 and decreased PaO2/FiO2 on admission were independent risk factors of mortality. Age and several comorbidities were related to longer hospital stay.
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Postgraduate medicine · Aug 2021
Editorial CommentManaging multiple myeloma during COVID-19: an ongoing saga.
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Postgraduate medicine · Jun 2021
Safety and tolerability of fixed-dose combinations of ibuprofen and acetaminophen: Pooled analysis of Phase 1-3 clinical trials.
An ibuprofen (IBU)/acetaminophen (APAP) fixed-dose combination (FDC) for over-the-counter (OTC) use was developed with the goal of providing the same effective analgesic activity as full doses of the individual monocomponents, while reducing individual monocomponent drug exposures. Here, the safety and tolerability of the FDC is characterized using pooled safety data from phase 1-3 clinical trials in the FDC development program. ⋯ NCT01559259; NCT02912650; NCT02837952; NCT02761980. The pharmacokinetic studies (n = 3) did not require registration.