Vestnik khirurgii imeni I. I. Grekova
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Vestn. Khir. Im. I. I. Grek. · Jan 2013
Comparative Study[The influence of modern plasma substitutes on the course of abdominal compartment syndrome in patients with abdominal sepsis].
The changes of intra-abdominal pressure (IAP) were followed up in 244 patients with abdominal sepsis after operation. The influence of liquid "resuscitation" with different types of plasma substitutes on the rates of IAP was studied and the dependence of changes IAP from filling of vascular bed was investigated. The impedance technique was used to determine the circulating blood volume and its percentage from proper index was estimated according to the sex, age and constitution. ⋯ The most severe ACS course was while using the crystalloid solutions in the complex of infusion therapy. The inclusion of colloids in the infusion therapy facilitated more full volume filling of vascular bed with the liquid, reduced the capillary leakage, accelerated the process of reduction of ACS. The advantage was shown by using the derivatives of hydroxyethylstarch, which promoted the elimination of deficiency of intravascular liquid in the best way.
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Vestn. Khir. Im. I. I. Grek. · Jan 2013
[Use of thrombin generation assay for the evaluation of coagulation and anticoagulant activity of hemostasis system in patients with abdominal sepsis].
Generally recognized factor, which complicates the course of sepsis, is the development of hypercoagulation syndrome. The increase of thrombin coagulation indicates on the elevation of risk of thrombus formation in microcirculation vessels, which could cause the formation of multiple organ failure. ⋯ The diagnosis of generalized peritonitis had 30 patients (18 men and 12 women, aged 61+/-18,3 years) and they were included in the research. It was shown, that the use of thrombin generation assay in patients with the abdominal sepsis could give the well-timed analysis of hypercoagulation changes and the assessment of protein C system investment in the thrombin generation.