Indian journal of physiology and pharmacology
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Indian J. Physiol. Pharmacol. · Apr 2005
Comparative StudyRegulation of cardiovascular functions during acute blood loss.
Sudden blood loss of moderate degree causes fall in blood pressure, which is compensated to certain extent by baroreceptor mediated rise in heart rate and vasoconstriction. In case of severe haemorrhage fall in blood pressure is accompanied by bradycardia indicating failure of baroreceptor mediated recovery in blood pressure. In such conditions partial recovery in the blood pressure with time is possible due to mechanisms other than baroreflex. ⋯ There was a recovery in cardiac output and mean arterial pressure with time in both the cases of blood loss. While a rise in heart rate and stroke volume was produced in 20% blood loss however an initial increase in stroke volume alone and later rise in heart rate alone was produced during recovery phase in 35% blood loss. These finding suggest that 20% blood loss is compensated by baroreflex while 35% blood loss is not accompanied by tachycardia so mechanisms other than the baroreflex, like increase in the vagal tone, contribute to the initial recovery in blood pressure and cardiac output.
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Indian J. Physiol. Pharmacol. · Jan 2005
Review Comparative StudyLung functions with spirometry: an Indian perspective--I. Peak expiratory flow rates.
Peak expiratory flow rate is an effective measure of effort dependent airflow. It is relatively a simple procedure, and may be carried out in the field using portable instruments. ⋯ Common regression equations for Indians enveloping major studies from various parts of the country have been formulated. Indian PEFR values compare favourably with other ethnic groups such as Americans and Europeans.
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Indian J. Physiol. Pharmacol. · Jan 2004
Effect of occupational noise on the nocturnal sleep architecture of healthy subjects.
Noise is considered to be a non-specific stressor which generally causes physiological and psychological effects in an individual. Many occupations involve workers being subjected to loud noise levels without adequate protective measures. The study was done to document the changes, if any, in the nocturnal sleep architecture of healthy persons exposed to loud occupational noise during daytime. ⋯ It can be concluded that workers exposed to loud background occupational noise are at an increased risk of having poor quality sleep but adaptation to this effect probably takes place after a few years.
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Indian J. Physiol. Pharmacol. · Oct 2003
Comparative StudyEffect of occupational noise on the nocturnal sleep architecture of healthy subjects.
Noise is considered to be a non-specific stressor which generally causes physiological and psychological effects in an individual. Many occupations involve workers being subjected to loud noise levels without adequate protective measures. The study was done to document the changes, if any, in the nocturnal sleep architecture of healthy persons exposed to loud occupational noise during daytime. ⋯ It can be concluded that workers exposed to loud background occupational noise are at an increased risk of having poor quality sleep but adaptation to this effect probably takes place after a few years.
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Indian J. Physiol. Pharmacol. · Jul 2003
Clinical TrialCardiorespiratory responses to submaximal incremental exercise are not affected by one night's sleep deprivation during the follicular and luteal phases of the menstrual cycle.
The purpose of the study was to investigate the effects of one night's sleep deprivation on the cardiorespiratory responses to exercise during the follicular and luteal phases of the menstrual cycle. We have studied nine, healthy females aged 24-35 years with regular menstrual cycles. Each subject performed spirometric tests at rest and then an incremental exercise testing during 11-13 days of follicular phase and 22-24 days of luteal phase following one normal night's sleep or one night's sleep loss. ⋯ Spirometric variables which include forced vital capacity (FVC), forced expiratory volume in one s (FEV1), FEV1/FVC%, forced expiratory volume in three s (FEV3), forced expired flow from 25-75% of FVC (FEF 25-75%), forced expired flow at 25% of FVC (FEF 25%), forced expired flow at 50% of FVC (FEF 50%), forced expired flow at 75% of FVC (FEF 75%), forced expired flow from 75-85% of FVC (FEF 75-85%), peak expiratory flow (PEF), expiratory reserve volume (ERV), inspiratory capacity (IC) and maximal voluntary ventilation (MVV) and cardiorespiratory variables were not different between the cycle phases after one normal night's sleep or one night's sleep deprivation. Neither menstrual cycle phase nor sleep deprivation affected spirometric and cardiorespiratory parameters. We suggest that one night's sleep deprivation does not produce alterations in spirometric parameters and cardiorespiratory responses to submaximal incremental exercise during the follicular and luteal phases.