Läkartidningen
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In a Swedish nationwide case-control study, gastroesophageal reflux and obesity were identified as strong and independent risk factors for esophageal adenocarcinoma. A moderately strong association was found with adenocarcinoma of the gastric cardia. No significant association was found with squamous cell carcinoma of the esophagus. ⋯ Our calculations revealed that even in the group with the highest risk, endoscopic surveillance is not readily recommended. Possible reasons for the increasing incidence of adenocarcinoma of the esophagus include 1) a suspected increase in the prevalence of reflux disease; 2) the increasing prevalence of obesity reported in western populations; and 3) the widespread use of medications that relax the lower esophageal sphincter and might cause reflux. All of these hypotheses suffer from inconsistencies that need to be solved before any firm conclusions can be drawn concerning the reasons for the increasing incidence of esophageal adenocarcinoma.
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Biography Historical Article
[Sigmund Freud discovered the therapeutic effects of cocaine, but all the credit went to Carl Koller].
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On the night of October 29, 1998, a fire broke out in an old warehouse in Gothenburg, where nearly 400 teenagers had gathered for a disco party. More than 200 patients were brought to four different hospitals in the region. Sixty-one people died at the scene due to inhalation of toxic fumes caused by the fire. ⋯ Thus, medical care at the scene was limited. The principle of OEload and go pi was used, placing the major burden of triage on the hospitals. The limited numbers of medical personnel and available supplies caused major stress for the physicians involved at the scene.