British journal of obstetrics and gynaecology
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Br J Obstet Gynaecol · Jul 1996
Prenatal genetic services for Down's syndrome: access and provision in 1990-1991. Steering Committee of the National Confidential Enquiry into Counselling for Genetic Disorders.
To examine access to and provision of prenatal genetic services relating to Down's syndrome. ⋯ The study has demonstrated that in 1990-1991: 1. There were certain shortcomings in the documentation of antenatal care; 2. Late booking was the main factor precluding the offer of prenatal diagnosis to women aged 38 or over, and 3. The rate of confirmation of Down's syndrome in terminated fetuses was incomplete.
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Br J Obstet Gynaecol · Jun 1996
Cardiac abnormalities in pulmonary oedema associated with hypertensive crises in pregnancy.
To describe the cardiac abnormalities by two-dimensional and Doppler echocardiography (echo-Doppler) in hypertensive crises in pregnancy (HCP) complicated by pulmonary oedema and identify pathogenic factors. ⋯ This study demonstrates the value of echo-Doppler to diagnose structural and functional cardiac abnormalities in HCP complicated by pulmonary oedema. The potential role of left ventricular diastolic filling abnormalities in the pathogenesis of pulmonary oedema complicating HCP is discussed.
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Br J Obstet Gynaecol · Apr 1996
Randomized Controlled Trial Comparative Study Clinical TrialA comparison of goserelin and danazol as endometrial thinning agents prior to endometrial laser ablation.
To compare the effectiveness of goserelin and danazol prior to endometrial laser ablation and assess different dosage regimens. ⋯ Goserelin appears to be more effective and better tolerated than danazol for treatment prior to endometrial laser ablation. Eight weeks treatment with goserelin resulted in better operating conditions and more vasomotor side effect, compared with four weeks treatment, although there was no difference in clinical outcome.
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Br J Obstet Gynaecol · Apr 1996
Randomized Controlled Trial Multicenter Study Comparative Study Clinical TrialA comparative study of safety and efficacy of continuous low dose oestradiol released from a vaginal ring compared with conjugated equine oestrogen vaginal cream in the treatment of postmenopausal urogenital atrophy.
To compare the safety, efficacy and acceptability of a continuous low dose oestradiol releasing vaginal ring with conjugated equine oestrogen vaginal cream in the treatment of postmenopausal urogenital atrophy. ⋯ With equivalent efficacy and safety and superior acceptability to vaginal cream, the low dose oestradiol vaginal ring is an advance in vaginal delivery systems for the treatment of urogenital atrophy.