Duodecim; lääketieteellinen aikakauskirja
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Children's limb fractures are commonly seen in general practice and emergency departments. Diagnostics relies on relevant clinical examination and good quality radiographs and will be supplemented with CT scanning, when necessary. ⋯ With operative treatment, rigid fixation of the fracture is not necessary; K-wires and elastic intramedullary nails are widely used. Although the aim of the treatment is exact positioning of the fracture, growing bone has a great capacity of remodeling, which may correct malposition.
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Endometrial ablation is a commonly used procedure in the treatment of heavy menstrual bleeding. The procedure is considered quite safe, but may also involve severe complications. We present a patient who developed life-threatening sepsis after the procedure.
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Practice Guideline
[Update on current care guidelines. The tendon disorders of the shoulder].
Degenerative rotator cuff tendon disease (tendinopathy) is the most common disorder of the shoulder. A full-thickness tear of the rotator cuff may be caused by degeneration, or it may develop due to an acute trauma. The typical symptoms include pain and functional deficiencies. ⋯ The primary radiologic imaging is x-ray. Degenerative tendon diseases are primarily treated conservatively in primary health care, the most important treatment modality is physiotherapy-guided therapeutic rehabilitation. Surgical treatment is considered in full-thickness rotator cuff tears, especially after traumatic onset.
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The recommendation to discharge low-risk pulmonary embolism patients from or after a brief monitoring in the emergency department has not been widely adopted in Finland. ⋯ A significant proportion of patients with pulmonary embolism can be treated on the outpatient basis.
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For more than a quarter century, the research of and drug development for Alzheimer's diseases have been governed by the amyloid plaque hypothesis, whereby deranged metabolism of the amyloid precursor protein leads to the formation of extracellular amyloid plaques, which in turn causes the activation of microglial cells, destruction of neurons and a progressive memory disease. The ending of three extensive clinical trials in disappointment has raised the question whether the amyloid plaque hypothesis is the correct starting point in the development of curative treatment for Alzheimer's disease at all. Two commencing new trials with patients that are still symptomless will be the final challenge for the hypothesis.