Pneumonologia i alergologia polska
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Pneumonol Alergol Pol · Jan 2007
[The relationship between markers of airway inflammation and thickness of the basement membrane in patients with asthma].
Airway inflammation and remodeling are well recognized features of asthma. Remodeling is usually regarded as a consequence of chronic inflammation, however there are also data suggesting that remodeling is a relatively independent process in asthma. Neither inflammation nor remodeling is a uniform process. Thus the precise relationship between markers of inflammation and different patterns of remodeling are still matter of investigations. The aim of the study was to assess the relationship between total and differential cell count in induced sputum (IS) and BALF, and thickness of the basement membrane (BM) in patients with stable asthma. ⋯ There was no relationship between BM thickness and total number of cells nor number of eosinophils in BALF and/or IS.