Zhongguo wei zhong bing ji jiu yi xue = Chinese critical care medicine = Zhongguo weizhongbing jijiuyixue
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Zhongguo Wei Zhong Bing Ji Jiu Yi Xue · Dec 2005
Randomized Controlled Trial[Clinical study of low molecular weight heparin therapy for sepsis].
To investigate the therapeutic effect of low molecular weight heparin (LMWH) therapy on sepsis. ⋯ LMWH can ameliorate sepsis by down-regulating the levels of pro-inflammatory cytokines, and suppressing the release of oxygen-derived free radicals. It is a promising treatment measure in sepsis patient with safety and no severe side effects.
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Zhongguo Wei Zhong Bing Ji Jiu Yi Xue · Dec 2005
[Study of continuous blood purification in severe pneumonia patients with multiple organ failure].
To review retrospectively the effect of continuous blood purification (CBP) on septic shock with acute renal failure and respiratory failure as a result of severe pneumonia, and to analyze its relationship with prognosis. ⋯ (1) CBP is curative for some patients in septic shock with acute renal failure and respiratory failure as a result of severe pneumonia, with and overall survival rate of 28%. (2) APACHE III score is a sensitive index before and after CBP treatment, and scores of 90-100 may be taken as an indication for CBP. (3) High blood sugar and fibrinogen levels may be potential risk factors, in particular, a high fibrinogen level implies a poor prognosis.
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Zhongguo Wei Zhong Bing Ji Jiu Yi Xue · Dec 2005
[Clinical study of relationship between serum procalcitonin and severity of multiple organ dysfunction syndrome].
To study the correlation between serum procalcitonin (PCT) level and severity of multiple organ dysfunction syndrome (MODS). ⋯ Serum PCT has clinical values in judgment of the severity of infected patients complicated by MODS.
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Zhongguo Wei Zhong Bing Ji Jiu Yi Xue · Dec 2005
[Effect of hydroxyethyl starch and Ringer's solution on splanchnic perfusion in dogs with septic shock].
To investigate the effect of 6% hydroxyethyl starch (HES) and Ringer's solution (RS) on splanchnic perfusion in dogs with septic shock. ⋯ Both HES and RS could improve MAP and DO(2) in dogs with septic shock, but the effect of HES was better than RS on splanchnic perfusion.
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Zhongguo Wei Zhong Bing Ji Jiu Yi Xue · Dec 2005
[Study on changes in inflammatory cytokines and the relationship to multiple organ injury in rats with aspiration lung injury after fire-arm injury].
To observe the phasic variations in concentrations of pro-inflammatory and anti-inflammatory cytokines, and to explore their potential roles in the occurrence and development process of multiple organ dysfunction. ⋯ Cytokines are the direct mediators for multiple organ failure (MOF), and MOF is triggered by TNF-alpha and a cascade of cytokine release, with a prolonged high-expression of IL-6. The loss of control of IL-4 aggravates the development of MOF.