Zhongguo wei zhong bing ji jiu yi xue = Chinese critical care medicine = Zhongguo weizhongbing jijiuyixue
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Zhongguo Wei Zhong Bing Ji Jiu Yi Xue · Apr 2011
Randomized Controlled Trial[Difference between single hole exhalation valve and plateau exhalation valve when used in patients treated with BiPAP Vision ventilator for chronic obstructive pulmonary disease with hypercapnia].
To observe difference in clinical effect between single hole exhalation valve and plateau exhalation valve when used in patients treated with BiPAP Vision ventilator for chronic obstructive pulmonary disease (COPD) with hypercapnia. ⋯ During BiPAP Vision ventilator in NIPPV treatment of patients with COPD complicated with CO2 retention , single hole exhalation valve and plateau exhalation valve both resulted in marked improvement in PaO2 and obvious decrease in PaCO2. Plateau exhalation valve corrected CO2 retention more quickly and effectively than side hole exhalation valve probably by preventing CO2 rebreathing by the patients.
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Zhongguo Wei Zhong Bing Ji Jiu Yi Xue · Apr 2011
Controlled Clinical Trial[The application of improved Glasgow coma scale score of 15 as switching point for invasive noninvasive mechanical ventilation in treatment of severe respiratory failure in chronic obstructive pulmonary disease].
To estimate the feasibility and the efficacy of early extubation and the sequential non invasive mechanical ventilation (MV) in severe respiratory failure of chronic obstructive pulmonary disease (COPD) with the improved Glasgow coma scale (GCS) score of 15 as the switching point. ⋯ The application of improved GCS score of 15 as the switching point with 2 hours as window period for early extubation and non invasive nasal mask ventilation can significantly improve the therapeutic effect in patients with severe respiratory failure in COPD.
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Zhongguo Wei Zhong Bing Ji Jiu Yi Xue · Apr 2011
[Effect of inhalation of aerosolized unfractioned heparin on peri alveolar coagulability and inflammatory response in endotoxin induced acute lung injury rat model].
To observe the local changes in alveoli in intravenous endotoxin induced acute lung injury (ALI) rat model after inhalation of aerosolized unfractioned heparin (UFH), and to observe its effects on coagulability, fibrinolysis and inflammatory response. ⋯ It was proved that inhalation of aerosolized UFH resulted in lowering local coagulability, alleviating fibrinolytic depression, improving fibrinolysis , and attenuating inflammation in endotoxin induced ALI rat model. More prominent results will be obtained when it was use as a prophylactic measure. The optimal time of usage is 6 hours after endotoxin injection.
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Zhongguo Wei Zhong Bing Ji Jiu Yi Xue · Apr 2011
Comparative Study[The effect of positive pressure ventilation combined with diaphragm pacing on respiratory mechanics in patients with respiratory failure].
To observe the effects of combining positive pressure ventilation with diaphragm pacing on respiratory mechanics in patients with respiratory failure. ⋯ Compared with positive pressure ventilation , positive pressure ventilation combined with diaphragm pacing can decrease the Paw, increase intrathoracic negative pressure, transpulmonary pressure, and Cst, and decrease WOBv, while there is no effect on Raw and R(L).
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Zhongguo Wei Zhong Bing Ji Jiu Yi Xue · Apr 2011
Controlled Clinical Trial[Study of the effects of mechanical ventilation on the heart function of patients with echocardiography].
To study the effects of different positive end expiratory pressure (PEEP) levels on the heart function of patients undergoing mechanical ventilation (MV) with echocardiography. ⋯ Under the same condition of MV, change in PEEP levels (0-14 cm H(2)O) do not produce any obvious effect in the normal cardiac function group, on the other hand when PEEP≥10 cm H(2)O left heart function is significantly lowered in the poor cardiac function group. Optimal PEEP may improve the cardiac function.