Zhongguo wei zhong bing ji jiu yi xue = Chinese critical care medicine = Zhongguo weizhongbing jijiuyixue
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Zhongguo Wei Zhong Bing Ji Jiu Yi Xue · Apr 2011
[Experimental study on acute respiratory distress syndrome and analysis of relevant factors in rabbits subjected to thoracic blast trauma].
To reproduce acute respiratory distress syndrome (ARDS) model in rabbit induced by chest blast injury and to analyze the pathogenesis and causes of early death in order to provide the basis for the early diagnosis of lung blast injury and its early warning system to facilitate an early treatment. ⋯ In an airtight environment, rabbit ARDS model can be reproduced successfully by blast injury with 1 917.3 mm Hg explosion pressure; TNF-α and IL-6 are involved in the pathogenesis and development of ARDS in blast injury. Pneumothorax as a result of lung rupture is the chief reason for early death and dysfunction of circulatory system is also an important reason in producing early death.
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Zhongguo Wei Zhong Bing Ji Jiu Yi Xue · Mar 2011
[Effect of hydroxyethyl starch on intracranial pressure and plasma colloid osmotic pressure in rats with cerebral ischemia/reperfusion injury].
To investigate the regulatory effect of hydroxyethyl starch on colloidal osmotic pressure (COP), and its effect on intracranial pressure (ICP) in rats with cerebral ischemia/reperfusion (I/R) injury. ⋯ Intravenous injection of hydroxyethyl starch 130/0.4 can increase the plasma COP, but it can not significantly reduce ICP and brain water content, and it also can not improve the neuronal apoptosis.
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Zhongguo Wei Zhong Bing Ji Jiu Yi Xue · Mar 2011
[A study of rate of compliance with sepsis bundle in patients with severe sepsis and septic shock in emergency department].
To evaluate the occurrence of severe sepsis and septic shock and the rate of compliance with sepsis bundle in patients with severe sepsis and septic shock in emergency department. ⋯ The incidence of severe sepsis and septic shock was high in emergency department, but the rate of recognition of it and the compliance with sepsis bundle were inadequate. It is urgently necessary to enhance the learning and implementation of the guideline.
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Zhongguo Wei Zhong Bing Ji Jiu Yi Xue · Mar 2011
[Prognostic value of N terminal pro B type natriuretic peptide in critically ill patients].
To investigate whether plasma N-terminal pro-B-type natriuretic peptide (NT-pro-BNP) as measured at admission to intensive care unit (ICU) is an independent predictor of mortality in critically ill patients. ⋯ The ICU NT-pro-BNP level higher than 1 418 ng/L and APACHEII score at admission are independent prognosis markers of early mortality. NT-pro-BNP might serve as a potent early diagnostic and prognostic marker in critically ill patients.
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Zhongguo Wei Zhong Bing Ji Jiu Yi Xue · Mar 2011
[Experimental study of a battlefield shock resuscitation fluid with new formula].
To propose a resuscitation fluid with a new formula for resuscitation of shock in battlefield on the basis of pathogenesis of hemorrhagic shock and clinical experiences, and to evaluate its safety and effectiveness in a rat hemorrhagic shock model. ⋯ The designed battlefield anti shock fluid in this study has been shown to be effective in fluid resuscitation for hemorrhage shock in rats, with reduced tissue edema and less injury to the liver, lung and intestine.