Zhongguo wei zhong bing ji jiu yi xue = Chinese critical care medicine = Zhongguo weizhongbing jijiuyixue
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Zhongguo Wei Zhong Bing Ji Jiu Yi Xue · Jan 2007
[Apoptosis of circulating lymphocyte in surgical critically ill patients associated with poor outcome].
To investigate the role and mechanism of lymphocyte apoptosis in post-operative critically ill patients and to determine the effects of lymphocyte apoptosis on the outcome of post-operative critically ill patients. ⋯ Lymphocyte apoptosis is enhanced in peripheral blood of post-operative critically ill patients and leads to a profound and persistent lymphopenia associated with poor outcome such as secondary infection and delay of ICU stay duration. Further studies are required to examine whether intervention to prevent lymphocyte apoptosis might alter the patients' outcome.
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Zhongguo Wei Zhong Bing Ji Jiu Yi Xue · Jan 2007
[Efficacy and safety of coupled plasma filtration adsorption combined with continuous veno-venous hemofiltration for multiple organ dysfunction syndrome patients with acute liver failure].
To evaluate efficacy and safety of coupled plasma filtration adsorption (CPFA) combined with continuous veno-venous hemofiltration (CVVH) for the treatment of multiple organ dysfunction syndrome (MODS) patients with acute liver failure (ALF), and to evaluate the effect of CPFA plus CVVF on inflammatory mediators in these patients. ⋯ Our data indicate that CPFA combined with CVVH is an effective and safe method to improve the prognosis of MODS patients with ALF, the mechanism of which may be related to its effective removal of inflammatory cytokines.
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Zhongguo Wei Zhong Bing Ji Jiu Yi Xue · Jan 2007
[Clinical evaluation of execution of early goal directed therapy in septic shock].
To evaluate the efficacy of early goal directed therapy (EGDT) in septic shock. ⋯ In the earlier period of septic shock, EGDT can remarkably decrease the patients'mortality and incidence of organ dysfunction, but can not improve survival rate and prognosis in patients in advanced stage of septic shock.
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Zhongguo Wei Zhong Bing Ji Jiu Yi Xue · Jan 2007
[Reproduction of a rat model of disseminated intravascular coagulation accompanied by multiple organ injuries].
To reproduce a rat model of disseminated intravascular coagulation (DIC) accompanied by multiple organ dysfunction syndrome (MODS) induced by endotoxin. ⋯ Double intravenous LPS challenge (98 microg/kg and 196 microg/kg) in rats can reproduce a rat model with DIC accompanied by multiple organ injuries.