Zhongguo wei zhong bing ji jiu yi xue = Chinese critical care medicine = Zhongguo weizhongbing jijiuyixue
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To study the effect of growth hormone (GH) on acute lung injury (ALI) induced by endotoxemia, and its potential therapeutic mechanism. ⋯ The application of GH during early stage of endotoxin challenge can deteriorate the lung injury induced by LPS through enhancing the expression and activation of NF-kappaB, thus enhances the inflammatory response in lungs.
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Zhongguo Wei Zhong Bing Ji Jiu Yi Xue · Aug 2005
Randomized Controlled Trial Comparative Study[Clinical comparative study of airway pressure release ventilation and continuous positive airway pressure ventilation].
To evaluate the effects of airway pressure release ventilation (APRV) and continuous positive airway pressure (CPAP) on hemodynamics, lung mechanics and oxygen metabolism index. ⋯ In APRV group sedation can be abstained during RM, and the hemodynamics were hardly disturbed. Improvement of lung mechanics and oxygenation is much better with APRV than CPAP mode.
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Zhongguo Wei Zhong Bing Ji Jiu Yi Xue · Aug 2005
Randomized Controlled Trial[Prospective randomized controlled clinical study of early use of noninvasive positive pressure ventilation in the treatment for acute exacerbation of chronic obstructive pulmonary disease].
To evaluate the effect of the early use of noninvasive positive pressure ventilation (NIPPV) on gas exchange, rate of endotracheal intubation and in-hospital mortality in patients with acute exacerbation of chronic obstructive pulmonary disease (COPD). ⋯ Early use of NIPPV can improve gas exchange, lessen respiratory muscle fatigue and decrease the need for intubation in patients with acute exacerbation of COPD.
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Zhongguo Wei Zhong Bing Ji Jiu Yi Xue · Aug 2005
Randomized Controlled Trial[Effects of lung recruitment maneuver on oxygenation and hemodynamics after open endotracheal suctioning in acute respiratory distress syndrome].
To evaluate the treatment value of lung recruitment (LR) maneuver on oxygenation and hemodynamics in acute respiratory distress syndrome (ARDS) patients after open endotracheal suctioning (ETS). ⋯ LR is effective in rapidly counteracting the deterioration in PaO(2) caused by open ETS in ARDS/ALI patients without interfering the hemodynamics.
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Zhongguo Wei Zhong Bing Ji Jiu Yi Xue · Aug 2005
Comparative Study[Role of prone position mechanical ventilation in patients with acute respiratory distress syndrome originating from pulmonary disease and extra-pulmonary disease].
To assess the effect of mechanical ventilation on prone position for the treatment of acute respiratory distress syndrome (ARDS) originating from pulmonary disease and extra-pulmonary disease. ⋯ Oxygenation is improved markedly in prone position in two groups. Mechanical ventilation on prone position was an effective method in the treatment of ARDS patients.