TheScientificWorldJournal
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TheScientificWorldJournal · Jan 2013
Bullying and its associated factors among school-aged adolescents in Thailand.
The aim of this study were to assess bullying and its associated factors in school-going adolescents in Thailand. Using data from the Thailand Global School-Based Student Health Survey (GSHS) 2008, the prevalence of being bullied and its associated factors among adolescents (N=2758) was assessed. ⋯ Among boys risk factors for having been bullied were younger age (adjusted odds ratio to (AOR): 0.34; 95% confidence interval (CI): 0.18-0.65), having been in a physical fight (AOR: 3.64; 95% CI: 2.84-4.66), being physically inactive (AOR: 1.49; 95% CI: 1.04-2.15), truancy (AOR: 1.66; 95% CI: 1.13-2.45), and psychosocial distress (AOR: 2.07; 95% CI: 1.14-3.74), and among girls risk factors for having been bullied were having been in a physical fight (AOR: 2.91; 95% CI: 2.00-4.24), lack of parental bonding (AOR: 0.71; 95% CI: 0.51-0.99), and psychosocial distress (AOR: 2.37; 95% CI: 1.39-4.03). Results may inform school health programmes on the prevalence and correlates of bullying among adolescents in Thailand.
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TheScientificWorldJournal · Jan 2013
The effects of dexmedetomidine on secondary acute lung and kidney injuries in the rat model of intra-abdominal sepsis.
In the present study, the effects of dexmedetomidine on secondary lung and kidney injuries were studied in the rat model of intra-abdominal sepsis by immunohistological and biochemical examinations. We measured serum creatinine, kidney tissue malondialdehide and plasma neutrophil gelatinase-associated lipocalin levels. ⋯ We demonstrated that dexmedetomidine attenuates sepsis-induced lung and kidney injuries and apoptosis in the rat model of sepsis. There is still need for comparative studies in order to determine the effects of dexmedetomidine on organ functions in early human sepsis.
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TheScientificWorldJournal · Jan 2012
Spinal anesthesia and minimal invasive laminotomy for paddle electrode placement in spinal cord stimulation: technical report and clinical results at long-term followup.
We arranged a mini-invasive surgical approach for implantation of paddle electrodes for SCS under spinal anesthesia obtaining the best paddle electrode placement and minimizing patients' discomfort. We describe our technique supported by neurophysiological intraoperative monitoring and clinical results. ⋯ Spinal cord stimulation under spinal anesthesia allows an optimal positioning of the paddle electrodes without any discomfort for patients or neurosurgeons. The best intraoperative positioning allows a better postoperative control of pain, avoiding the risk of blind placements of the paddle or further surgery for their replacement.
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TheScientificWorldJournal · Jan 2012
Increased NTPDase activity in lymphocytes during experimental sepsis.
We investigated in rats induced to sepsis the activity of ectonucleoside triphosphate diphosphohydrolase (NTPDase; CD39; E. C. 3.6.1.5), an enzyme involved in the modulation of immune responses. After 12 hours of surgery, lymphocytes were isolated from blood and NTPDase activity was determined. ⋯ Histological analysis showed several morphological changes in the septic group, such as vascular congestion, necrosis, and infiltration of mononuclear cells. It is known that the intracellular milieu contains much more ATP nucleotides than the extracellular. In this context, the increased ATPasic activity was probably induced as a dynamic response to clean up the elevated ATP levels resulting from cellular death.
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TheScientificWorldJournal · Jan 2012
ReviewBrain metastases research 1990-2010: pattern of citation and systematic review of highly cited articles.
High and continuously increasing research activity related to different aspects of prevention, prediction, diagnosis and treatment of brain metastases has been performed between 1990 and 2010. One of the major databases contains 2695 scientific articles that were published during this time period. Different measures of impact, visibility, and quality of published research are available, each with its own pros and cons. For this overview, article citation rate was chosen. ⋯ A large variety of preclinical and clinical topics achieved high numbers of citations. However, areas such as quality of life, side effects, and end-of-life care were underrepresented. Efforts to increase their visibility might be warranted.