British medical journal (Clinical research ed.)
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Br Med J (Clin Res Ed) · Feb 1984
Letter Case ReportsDanger of dead space in U100 insulin syringes.
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Br Med J (Clin Res Ed) · Feb 1984
Case ReportsMeningococcal septicaemia treated with combined plasmapheresis and leucapheresis or with blood exchange.
Mortality among patients suffering from meningococcal septicaemia has reached nearly 50% in parts of northern Norway despite intensive care. The activation of complement and blood cells by endotoxin is assumed to be the cause of most of the associated pathophysiological changes. ⋯ All recovered without sequelae, and no complications or serious problems caused by these procedures were observed. It is concluded that either combined leucapheresis and plasmapheresis or blood exchange is well tolerated and a valuable supplement to conventional intensive care in fulminant meningococcal septicaemia.