Zhonghua yi xue za zhi
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Zhonghua yi xue za zhi · Mar 2007
[Effect of propofol on synaptic long-term potentiation in hippocampal slices of rats].
To investigate the effect of propofol on the synaptic long-term potentiation (LTP) in the CA(1) area of rats hippocampal slices and the possible mechanisms of its effect, and to elucidate the mechanisms underlying the effect of propofol on memory. ⋯ The inhibition of LTP induction in hippocampus of rats may contribute to propofol-induced deficits in memory, and the underlying mechanism is involved in the activation of GABA(A) receptor other than GABA(B) receptor.
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Zhonghua yi xue za zhi · Mar 2007
Clinical Trial[Effect of intestinal electrical stimulation on small bowel transit: experiment with healthy volunteers].
To investigate the effect of intestinal electrical stimulation (IES) on small bowel transit. ⋯ IES is capable of accelerating small bowel transit with no effect on dyspeptic symptoms, which suggests that IES may be a potential therapeutic method on intestinal motility disorders.
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To explore the clinical application of the transplantation of the Meek autograft. ⋯ Meek autograft is suitable for all of the full-thickness wound except bone-exposure wound, including the wound of major burns. This technique uses less skin to repair the wound and the time for epithelization is shorter than that of the traditional methods. The staff and time needed for the operation are less. The outcome is good and the healed wound is fine-looking.
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Zhonghua yi xue za zhi · Mar 2007
[Autologous mononuclear bone marrow cell transplantation by intracoronary route for patients with ischemic heart disease: observation of 2-years follow-up].
To investigate the long-term effect and safety of intracoronary autologous bone marrow mononuclear cell (BMMC) transplantation in patients with ischemic heart disease (IHD). ⋯ Autologous BMMC intracoronary transplantation is safe and effective, especially in patients with CIHF.
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Zhonghua yi xue za zhi · Mar 2007
[Folate-poly-L-lysine-Gd-DTPA as MR contrast agent for tumor imaging via folate receptor-targeted delivery].
To study folate-conjugated Gd-DTPA-Poly-L-Lysine (folate-PL-Gd-DTPA) as MR targeting agent to tumor cells via folate receptor, to evaluate feasibility and effectiveness by observing MR signal variations and imaging feature of pulmonary tumor xenografts in nude mice using this contrast material. ⋯ Folate-PL-Gd-DTPA could be combined to tumor cells appetencially via folate receptor and significantly targeted to tumor cells with rich folate receptors for MR imaging.