Zhonghua yi xue za zhi
-
Zhonghua yi xue za zhi · Feb 2009
[Bone morphogenetic protein type II receptor gene promoter mutation-142G > A in a patient with familial pulmonary arterial hypertension].
To investigate the relation between bone morphogenetic protein type II receptor (BMPR2) gene promoter mutation and pulmonary arterial hypertension (PAH). ⋯ BMPR2 promoter mutation -142G > A may be associated with FPAH.
-
Zhonghua yi xue za zhi · Feb 2009
Controlled Clinical Trial[Relationship of serum Chemerin to obesity and type 2 diabetes mellitus].
To detect the serum Chemerin levels in patients with obesity and newly diagnosed type 2 diabetes mellitus (T2DM) and explore the relationship of serum Chemerin to body fat parameters, glucose and lipid metabolism, and insulin resistance index (IR). ⋯ Serum Chemerin levels are much higher in females and obese subjects are much higher than in men and subjects with normal weight. Serum Chemerin is correlated with insulin level, body fat disposition and lipid metabolism which suggesting that it may play a role in the pathophysiology of obesity and metabolic syndrome.