Zhonghua yi xue za zhi
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Zhonghua yi xue za zhi · Dec 2012
[Acute kidney injury early after cardiac surgery with cardiopulmonary bypass: clinical analysis].
To explore the occurrence of acute kidney injury (AKI) in early stage after cardiac surgery under cardiopulmonary bypass (CPB) and discuss the perioperative risk factors and its impact on clinical outcome. ⋯ As a common complication after cardiac surgery, AKI is associated with many perioperative risk factors. And the AKI classification is predicator of delayed extubation, extubation failure and death.
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Zhonghua yi xue za zhi · Dec 2012
[Mutation in the UBIAD1 gene of a Chinese family with Schnyder crystal corneal dystrophy].
To investigate the genetic feature of Schnyder corneal dystrophy identified in a four-generation Chinese family. ⋯ The missense mutation c.305A > G(p.Asn102Ser) of UBIAD1 gene may cause the disease of the family. Gene screen can assist clinicians in making definitive diagnosis, presymptomatic diagnosis and prenatal diagnosis.
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Zhonghua yi xue za zhi · Dec 2012
Meta Analysis[Whole brain radiation therapy plus temozolomide in the treatment of brain metastases from non small cell lung cancer: a meta-analysis].
To explore the efficacy and safety of whole brain radiation therapy (WBRT) plus temozolomide (TMZ) versus WBRT alone in the treatment of brain metastases from non-small cell lung cancer (NSCLC) through a meta-analysis. ⋯ For the treatment of brain metastases from NSCLC, the combined therapy of WBRT plus TMZ improves OR, but without significant improvement in OS. And the incidence of myelosuppression is elevated. Future large-scale, high-quality and prospective phase III RCTs are needed to confirm the clinical efficacy and safety of WBRT plus TMZ.
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Zhonghua yi xue za zhi · Dec 2012
[Timing of treatment on the prognosis of poor-grade aneurysmal subarachnoid hemorrhage patients].
To explore the prognostic effects of ultra-early, early, medium-term and late treatments of poor-grade aneurysm patients. ⋯ For patients of WFNS IV grade, the treatment should be performed as soon as possible. For patients in WFNS V grade, ultra-early and early treatments fare better than medium-term and late treatments. The mortality of medium-term treatment is the highest. Overall prognosis of late treatment has the worst outcome. Regardless of treatment period, conservative treatment shows the worst prognosis and the highest mortality.