Casopís lékar̆ů c̆eských
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Casopís lékar̆ů c̆eských · Mar 1989
[Electric stimulation of auditory nerve fibers. Experimental study].
The authors tested in animal experiments the effectiveness of electrical stimulation of acoustic nerve fibres. To guinea pigs platinum-iridium electrodes were implanted in the round window of the cochlea. The receptors of the inner ear were functionally eliminated by the local application of the ototoxic antibiotic gentamicin. ⋯ This relationship was the same for extracochlear and intracochlear stimulation, the absolute threshold values of the current in the same animal were, however, as a rule lower on intracochlear stimulation. The dynamic range of responses to electrical stimulation (difference between threshold intensity of the current and the intensity which produces a painful response of the animal) was 6-20 dB, as compared with 80-100 dB of the dynamic range for acoustic stimulation. The results of the experiments were used in the preparation of the Czechoslovak cochlear neuroprosthesis and serve as a basis for the further development of the implant.
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82 patients treated at a ward of anaesthesiology and resuscitation had 330 renal function tests performed using a computerized programme. While glomerular functions were often preserve or even increased, tubular functions displayed a broad spectrum of disorders. --Nosocomial effects may have a significant role to play there. ⋯ Tubular osmotic diuresis and overflow osmotic diuresis are the most frequent types of diuresis, while lower frequency is seen in water diuresis, mixed water and tubular osmotic diuresis, and mixed overflow and tubular osmotic diuresis. The therapeutical effects of the incidence of overflow osmotic diuresis and wider use of aldosterone antagonists are discussed.
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Casopís lékar̆ů c̆eských · Apr 1988
Historical Article[The coat of arms of the Prague Guild of Surgeons].