Revista Brasileira de terapia intensiva
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To evaluate and understand the clinical implications of the plasma levels of a soluble isoform of a receptor for advanced glycation end products (sRAGE) in different stages of sepsis. ⋯ sRAGE levels are associated with worse outcomes in patients with septic shock. However, a statistical correlation analysis with other proinflammatory cytokines indicated that the pathways leading to those outcomes are different depending on the sRAGE levels. Future studies to elucidate the pathophysiological mechanisms involving sRAGE in models of sepsis are of great clinical importance for the safe handling of this biomarker.
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Rev Bras Ter Intensiva · Oct 2014
Adherence to the items in a bundle for the prevention of ventilator-associated pneumonia.
To assess adherence to a ventilator care bundle in an intensive care unit and to determine the impact of adherence on the rates of ventilator-associated pneumonia. ⋯ The educational intervention performed in this study increased the adherence to the ventilator care bundle, but the incidence of ventilator-associated pneumonia did not decrease in the small sample that was assessed.
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Rev Bras Ter Intensiva · Oct 2014
Comparative StudyIneffectiveness of using the pressure relief valve technique during cuff inflation.
To test the effectiveness of using a cuff pressure relief valve technique to maintain cuff pressure levels within the normal in vitro range (Phase 1) in patients admitted to the intensive care unit (Phase 2) and to test the reproducibility of the technique using different syringes. ⋯ The use of syringes is not an effective technique for determining the cuff pressure in patients admitted to the intensive care unit.
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Rev Bras Ter Intensiva · Oct 2014
Septic versus non-septic acute kidney injury in critically ill patients: characteristics and clinical outcomes.
This study aimed to describe and compare the characteristics and clinical outcomes of patients with septic and non-septic acute kidney injury. ⋯ Sepsis was an independent predictor of death. Significant differences were found between the characteristics and clinical outcomes of patients with septic versus non-septic acute kidney injury.
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Rev Bras Ter Intensiva · Oct 2014
Case ReportsAssistance of inhalation injury victims caused by fire in confined spaces: what we learned from the tragedy at Santa Maria.
On January 2013, a disaster at Santa Maria (RS) due to a fire in a confined space caused 242 deaths, most of them by inhalation injury. On November 2013, four individuals required intensive care following smoke inhalation from a fire at the Memorial da América Latina in São Paulo (SP). The present article reports the clinical progression and management of disaster victims presenting with inhalation injury. ⋯ To conclude, inhalation injury has a preponderant role in fires in confined spaces. Invasive ventilation should not be delayed in cases with significant airway swelling. Hyperoxia should be induced early asa therapeutic means against carbon monoxide poisoning, in addition to empiric pharmacological treatment in suspected cases of cyanide poisoning.