Revue médicale suisse
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Revue médicale suisse · Jun 2008
[News in diagnostic and treatment of complex regional pain syndrome].
The complex regional pain syndrome (previously called algodystrophy) remains difficult to diagnose and to treat. New diagnostic criteria, easy to apply, based on patient's reports and clinical examination, have recently been proposed and deserve a large diffusion. ⋯ In particular, a rehabilitation program combining laterality recognition, mental imagery and mobilisation in front of a mirror showed a significant improvement of pain and functional capacities in a randomised, controlled, single blind study. This treatment is noninvasive, cheap, has no severe complications and favors patients autonomy.
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We present the case of a end stage renal failure patient treated with haemodialysis who developed painful nodules of the subcutis which progressed to ulcerative and necrotic lesions, gradually spreading. The diagnosis of calcific uremic arteriolopathy was made, based on histologic findings showing adipose tissue with necrotic areas and calcifications of the arterioles's media. We describe the clinical presentation of this syndrome which is associated with a high mortality and resume the actual conceptions about the pathogenesis, the diagnosis, prevention and treatment.
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Revue médicale suisse · Apr 2008
Review[The biological treatments for moderate to severe plaque psoriasis].
Psoriasis is a chronic inflammatory skin disorder that can cause substantial disability. The recognition of psoriasis as an immunologically mediated disease led to the development of agents that specifically target key steps in the pathological process. In this review, we focus on the mechanism of action, the efficacy and the safety data of the new biological treatments: alefacept, efalizumab, etanercept, infliximab and adalimumab.