Canadian Anaesthetists' Society journal
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The anaesthetic management of cardiopulmonary bypass (CPB) for a patient with biopsy-proven malignant hyperthermia is reported. Specific changes in the technique used, such as venting the oxygenator before use, monitoring mixed venous PO2 and PCO2, as well as the safety of cold hyperkalaemic cardioplegia are described. ⋯ We chose to treat left ventricular dysfunction by aggressive vasodilator (nitroglycerine) therapy. We detected no myocardial or respiratory depression secondary to dantrolene therapy either before or after operation.
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Linear airway dimensions from incisor teeth to vocal cords were measured from radiographs. Normal children were slightly taller and heavier than children being treated for cleft palate and had significantly longer upper airway dimensions. ⋯ Data from normal children in these two studies were used to calculate the distance from lips to mid-trachea to determine optimal length for a tracheal tube. Previously published data on airway lengths in children are reviewed.
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The question posed for this study was: "While holding a watching brief during an uneventful intra-abdominal surgical procedure do anaesthetics adopt the same position in the operating room with reference to the patient's head and "anaesthetic machine" and, if they do, what is it?" A study of the relative positions of the patient, the anaesthetist, and the "anaesthetic machine" during routine laparotomy showed great variation. The implication was that there was also great variation in the amount of movement necessary by the anaesthetist if the same amount of information was to be obtained with the same frequency. The significance of this with reference to the quality of patient care is discussed. The role of changes in apparatus and the declared need for this by anaesthetics is mentioned and recommendations regarding the visual acquisition of data during anaesthesia are made.
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In rat experiments, the relative potency an safety of thiopentone, diazepam and etomidate were assessed using different indices of anaesthesia - loss of righting reflex, prevention of movement and heart rate responses to an noxious stimulus. Log-probit dose-response curves for these end-points and for lethal effect were determined. Etomidate proved to be more potent than thiopentone or diazepam; its relative potency figures varied from 5 to 18 with the use of different end-points of anaesthesia. ⋯ The extreme variability in assessment of relative potency and safety with different end-points of anaesthesia probably indicates that the indices used reflected various components of anaesthesia. It seems likely that for the proper assessment of the potency of intravenous anaesthetics, one index of potency is not sufficient. Several indices of potency corresponding to different components on general anaesthesia must be used.