Conference proceedings : ... Annual International Conference of the IEEE Engineering in Medicine and Biology Society. IEEE Engineering in Medicine and Biology Society. Annual Conference
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Conf Proc IEEE Eng Med Biol Soc · Jan 2006
Heat transfer model of hyporthermic intracarotid infusion of cold saline for stroke therapy.
A 3-dimensional hemispheric computational brain model is developed to simulate infusion of cold saline in the carotid arteries in terms of brain cooling for stroke therapy. The model is based on the Pennes bioheat equation, with four tissue layers: white matter, gray matter, skull, and scalp. ⋯ The finite difference method was employed to solve the system of partial differential equations. This model demonstrated a reduction in brain temperature, at the stroke lesion, to 32 degrees C in less than 10 minutes.
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Conf Proc IEEE Eng Med Biol Soc · Jan 2006
Development and implementation of a biomedical information network.
Once the requirement for a biomedical information network has been articulated, the process of development and implementation can then be approached. Although the general architecture of such a system may appear to be self evident, there are careful design considerations that will allow the network to be robust and achieve increased levels of functionality as additional systems come on-line and become integrated into the network. ⋯ We have chosen the Emergin Orchestrator product (Boca Raton, Fl) as the vehicle for integrating these systems. The major design and implementation tasks include defining the basic information architecture, assessing the performance of the existing IT infrastructure, and understanding the native capabilities and limitations of each system involved in the network.
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Conf Proc IEEE Eng Med Biol Soc · Jan 2006
Quantitative EEG assessment of brain injury and hypothermic neuroprotection after cardiac arrest.
In this paper we provide a quantitative electroencephalogram (EEG) analysis to study the effect of hypothermia on the neurological recovery of brain after cardiac arrest. We hypothesize that the brain injury results in a reduction in information of the brain rhythm. To measure the information content of the EEG a new measure called information quantity (IQ), which is the Shannon entropy of decorrelated EEG signals, is developed. ⋯ In addition, EEG signal recovery under normothermic (37 degrees C) and hypothermic (33 degrees C) resuscitation following 5, 7 and 9 minutes of cardiac arrest is recorded and analyzed. Experimental results show that the IQ is higher for hypothermic than normothermic rats. The results quantitatively support the hypothesis that hypothermia accelerates the recovery of brain injury after cardiac arrest.
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Conf Proc IEEE Eng Med Biol Soc · Jan 2006
Using a generalized neural network to identify airway obstructions in anesthetized patients postoperatively based on photoplethysmography.
Photoplethysmography has been recently studied asa non-invasive indicator of circulatory and respiratory function. In this study, photoplethysmographic (PPG) data were recorded from patients under the influence of anesthesia, but not intubated. ⋯ This classifier considers inter-subject variability so that it generalizes well to a large population. This classifier provided 86.1%accuracy to classify segments as being times of 'obstructed' vs.'normal' airways status.