Conference proceedings : ... Annual International Conference of the IEEE Engineering in Medicine and Biology Society. IEEE Engineering in Medicine and Biology Society. Annual Conference
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Conf Proc IEEE Eng Med Biol Soc · Jan 2010
Development of modified intraoperative examination monitor for awake surgery (IEMAS) system for awake craniotomy during brain tumor resection.
Gliomas represent the most frequent type of primary intracranial tumors, which originate from the brain tissue itself, have infiltrative growth, unclear borders, and usually affect functionally-important cerebral structures. From March 2000 till March 2010, 839 neurosurgical procedures directed on resection of such neoplasms were performed in the intelligent operating theater of Tokyo Women's Medical University with the use of intraoperative MRI, real-time updated neuronavigation system, and Hi-vision operative microscope. To facilitate maximal possible tumor resection with minimal risk of neurological morbidity a special device, called Intraoperative Examination Monitor for Awake Surgery (IEMAS) was developed by us. ⋯ The clinical testing of t- - his system was initiated on February 1, 2010, but quickly revealed crossed line effect between transmitters and receivers. To overcome this obstacle and to isolate transmitters, one channel was changed from wireless connection into wired, which resulted in significant improvement of the clearness of both transmitted images and sounds, and provides an opportunity for effective clinical use of the device. In perspective we wish to make IEMAS system fully wireless, using several types of frequency range transmitters.
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Conf Proc IEEE Eng Med Biol Soc · Jan 2010
Development of a data acquisition and analysis system for nociceptive withdrawal reflex and reflex receptive fields in humans.
A system for data acquisition and analysis of nociceptive withdrawal reflex (NWR) and reflex receptive field (RRF) is introduced. The system is constituted by hardware and software components. ⋯ These programs were developed to maximize the potential of the hardware, turning it into a complete stimulation system capable of automatic quantification of NWR and RRF. In this article, a brief review of NWR and RRF analysis is presented, the system features are described in detail and its present and future applications are discussed.
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Conf Proc IEEE Eng Med Biol Soc · Jan 2010
Non lineal respiratory systems mechanics simulation of acute respiratory distress syndrome during mechanical ventilation.
Model and simulation of biological systems help to better understand these systems. In ICUs patients often reach a complex situation where supportive maneuvers require special expertise. ⋯ This work presents a model which can be simulated and use to help in training of physicians and respiratory therapists to analyze the respiratory mechanics in this kind of patients. We validated the model in 2 ARDS patients.
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Conf Proc IEEE Eng Med Biol Soc · Jan 2010
Merging PK/PD information in a minimally parameterized model of the neuromuscular blockade.
A recursive system identification algorithm that merges PK/PD information in a minimally parameterized Wiener model for the NMB level is presented. The results show that the coupling between one parameter from the linear block and one from the static nonlinearity is advantageous, when evaluated on a database of 60 real collected NMB cases.
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Conf Proc IEEE Eng Med Biol Soc · Jan 2010
Steering deep brain stimulation fields using a high resolution electrode array.
Deep brain stimulation (DBS) therapy relies on electrical stimulation of neuronal elements in small brain targets. However, the lack of fine spatial control over field distributions in current systems implies that stimulation easily spreads into adjacent structures that may induce adverse side-effects. ⋯ Our computational analysis demonstrates that the DBS-array is capable of accurately displacing activation volumes with sub-millimeter precision. Our findings demonstrate that future systems for DBS therapy may provide for more accurate target coverage than currently available systems achieve.