Conference proceedings : ... Annual International Conference of the IEEE Engineering in Medicine and Biology Society. IEEE Engineering in Medicine and Biology Society. Annual Conference
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Conf Proc IEEE Eng Med Biol Soc · Jan 2014
Computational modeling analysis of a spinal cord stimulation paddle lead reveals broad, gapless dermatomal coverage.
Spinal cord stimulation (SCS) is an effective therapy for treating chronic pain. The St. Jude Medical PENTA(TM) paddle lead features a 4 × 5 contact array for achieving broad, selective coverage of dorsal column (DC) fibers. ⋯ We found that across contact configurations used clinically in the sweep algorithm, the activation region shifted smoothly between left and right DC, and could achieve gapless medio-lateral coverage in dermatomal fiber tract zones. Increasing stimulation amplitude between the DC threshold and discomfort threshold led to a greater area of activation and number of dermatomal zones covered on the left and/or right DC, including L1-2 zones corresponding to dermatomes of the lower back. This work demonstrates that the flexibility in contact selection offered by the PENTA lead may enable patient-specific tailoring of SCS.
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Conf Proc IEEE Eng Med Biol Soc · Jan 2014
Interaction between EEG and drug concentration to predict response to noxious stimulation during sedation-analgesia: effect of the A118G genetic polymorphism.
The level of sedation in patients undergoing medical procedures is affected by the interaction between the effect of the anesthetic and analgesic agents and the pain stimuli. The presence of the A118G single nucleotide polymorphism (SNP) in the OPRM1 gene affects the requirements of opioids for patients undergoing sedation-analgesia. ⋯ The proposed measures were based on power spectral density and auto-mutual information function. It was found that the statistical performances of the EEG measures improved when the presence of the SNP was taken into account (prediction probability Pk>0.9).
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Conf Proc IEEE Eng Med Biol Soc · Jan 2014
Signal quality quantification and waveform reconstruction of arterial blood pressure recordings.
Arterial blood pressure (ABP) is an important vital sign of the cardiovascular system. As with other physiological signals, its measurement can be corrupted by different sources of noise, interference, and artifact. Here, we present an algorithm for the quantification of signal quality and for the reconstruction of the ABP waveform in noise-corrupted segments of the measurement. ⋯ In segments of poor signal quality, the ABP wavelets are then reconstructed on the basis of the expected cycle duration and envelope information derived from neighboring ABP wavelet segments. The algorithm was tested on two datasets of ABP waveform signals containing both invasive radial artery ABP and noninvasive ABP waveforms. Our results show that the approach is efficient in identifying the noisy segments (accuracy, sensitivity and specificity over 95%) and reliable in reconstructing beats that were artificially corrupted.
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Conf Proc IEEE Eng Med Biol Soc · Jan 2014
Assessing the privacy policies in mobile personal health records.
The huge increase in the number and use of smartphones and tablets has led health service providers to take an interest in mHealth. Popular mobile app markets like Apple App Store or Google Play contain thousands of health applications. Although mobile personal health records (mPHRs) have a number of benefits, important challenges appear in the form of adoption barriers. ⋯ The results show important differences in both the mPHRs and the characteristics analyzed. A questionnaire containing six questions concerning privacy policies was defined. Our questionnaire may assist developers and stakeholders to evaluate the security and privacy of their mPHRs.
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Conf Proc IEEE Eng Med Biol Soc · Jan 2014
Localization of subthalamic nucleus borders using macroelectrode local field potential recordings.
Deep brain stimulation of the subthalamic nucleus (STN) is a highly effective treatment for motor symptoms of Parkinson's disease. However, precise intraoperative localization of STN remains a procedural challenge. In the present study, local field potentials (LFPs) were recorded from DBS macroelectrodes during trajectory to STN, in six patients. ⋯ For these sub-bands, RMS of these distances was found to be 1.26 mm and 1.06 mm, respectively. Analysis of other sub-bands did not allow for distinguishing the caudal border of STN. In conclusion, macroelectrode-derived LFP recordings may provide an alternative approach to MER-SUA, for localizing the target STN borders during DBS surgery.