Revista médica de Chile
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Revista médica de Chile · Sep 2019
[Use of sodium-glucose cotrasporter 2 inhibitors in type 2 diabetics. Experience in 77 patients].
Sodium-glucose cotransporter 2 inhibitors (SGLT2i) are a new pharmacological alternative for the treatment of diabetes. ⋯ The effects observed in this study are comparable and of similar magnitude to randomized studies of SGLT2i reported in the international literature.
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Revista médica de Chile · Sep 2019
[Spontaneous dissection of visceral arteries. A series of cases].
Spontaneous dissections of visceral arteries are rare and usually secondary to other disease. There is paucity of information about their natural course. ⋯ In this series of patients, spontaneous dissection of visceral arteries had a benign, favorable course, requiring only conservative management.
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Revista médica de Chile · Sep 2019
[Lifestyles of Chilean housewives. Analysis of the 2009-2010 Chilean Health Survey].
Housewives represent a important proportion of the Chilean population. However, there is limited evidence about their lifestyles. ⋯ Housewives had high levels of central obesity, excess body weight and high levels of salt intake but low alcohol intake. Their healthy lifestyles behaviors increased along with increasing age.
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Revista médica de Chile · Sep 2019
[The presence of women in Chilean medicine: from the times of Eloísa Díaz to this day].
Though the presence of many women in medicine goes unnoticed today, their incorporation to the field was slow and difficult. It took until the end of the nineteenth century for women to be finally allowed to study at the University in Chile, being Eloísa Díaz the first woman to become a medical doctor in 1887. In that century, only six women became medical doctors. ⋯ At present, women doctors constitute 40% of the total pool of medical doctors in Chile, being present in all specialties, though preferably found as general practitioners, family doctors and pediatricians. While many women have stood out in academia and in politics, they have also successfully reached high positions in scientific societies (and other offices such in the Health Ministry, and even the country's presidency) their participation is still limited in these areas. It is only fair to conclude that the outstanding participation that women in Chilean medicine enjoy today is not solely due to their long-lasting efforts, but more importantly, to their tireless struggle to overcome prejudice, discrimination and misunderstanding; the latter being especially represented by pioneer women of medicine.
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Revista médica de Chile · Sep 2019
[Prion induced spongiform encephalopathy of Creutzfeldt-Jakob disease].
The infectious protein or prion (PrPSC) is a transmissible and replicable polypeptide, which arises from an abnormal folding of the PrP protein, by unknown mechanisms and without changes in the primary sequence of its amino acids. Its new spatial disposition arises from the substitution of its alpha helices by beta bands, which increase its structural stability, avoiding its complete proteolysis, resulting in a residual accumulation of prions. These prions induce the misfolding of normal PrP protein, generating their exponential increase, leading to a disturbance of neuronal homeostasis which results in the development of the fatal spongiform encephalopathy of the Creutzfeldt-Jakob disease (CJD). ⋯ The Classical form of CJD produced by MM1 prion occurs in 70% of the cases. The Cerebellar form originated by the VV2 prion occurs in 15% of cases, the form with Kuru plates, associated with the prion MV2 occurs in 5%, and the Vacuolar, related to the MM2 prion occurs in 4%. CJD is always characterized by behavioral, motor, cognitive, and vision alterations and by findings in magnetic resonance imaging, electroencephalogram and cerebrospinal fluid that define each clinical and neuropathological form.