Revista médica de Chile
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Revista médica de Chile · Mar 2023
[New technological strategies for drug administration in the treatment of joint pathologies].
Despite the availability of drugs and pharmaceutical forms for the treatment of rheumatoid arthritis and osteoarthritis symptoms, their adverse effects and lack of response to therapy reinforces the need to search for new technological formulation strategies capable of delaying the progress of the disease, with better therapeutic results and prolonged control of arthropathy. The aim of this bibliographic review was to identify new reported therapeutic approaches for these diseases. ⋯ Thus, the new therapies aim to suppress inflammatory mediators and to reduce the degradation of the extracellular matrix. In addition, the use of nano and microtechnology takes advantage of the properties of polymers, lipids, peptides, and nucleic acids to develop controlled drug release systems, aiming to obtain highly effective precision therapies, whose usefulness should be evaluated in future clinical trials.
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Revista médica de Chile · Mar 2023
[The impact of the different waves of COVID-19 pandemic in Chile across regions].
The effects of COVID-19 in Chile changed over time and among regions. ⋯ These results emphasize the need to consider regional differences and the temporal context for the elaboration of strategies to the efficient management of a pandemic.
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Revista médica de Chile · Mar 2023
Food insecurity in Chilean university students during the COVID-19 pandemic.
Food and nutrition were affected by the COVID-19 pandemic, increasing levels of food insecurity. University students were a risk group for food insecurity due to the closure of educational establishments where they received their main meals. ⋯ Undergraduate students are vulnerable to food insecurity. Mitigation actions should be carried out when educational establishments are closed.
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Revista médica de Chile · Mar 2023
Observational Study[Use of medicinal plants among older people attending a public primary care center].
The use of medicinal plants is common among a significant part of the elderly population. In addition, at present, the use of medicinal plants has been introduced in Primary Health Care centers, and is becoming increasingly popular, especially in this population. ⋯ The results reinforce the importance of knowing the plant species used by the population and the correct orientation on their rational use, potential benefits, adverse effects and interactions.