The Pan African medical journal
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The Ebola Virus Disease (EVD) in West Africa has stimulated investments in EVD research. While these research efforts are most welcome, we are concerned about the potential to ignore effective community ethics engagement programmes and critical government regulatory agencies in light of the urgency to conduct clinical trials for EVD therapies and vaccines. We discuss the reasons why community engagement with various research stakeholders is essential, how community engagement should be conducted, and the potential consequences of failing to engage both communities and regulatory agencies by drawing on past experiences in the field of HIV research. We highlight the importance of a) capacity building to enable local researchers design and implement EVD research for future epidemics, b) the need to support community research literacy, and c) the need to build the competency of research regulatory agencies on the continent to address EVD therapy and vaccine research.
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Strategies to transfer international health research training programs to sub-Saharan African institutions focus on developing cadres of local investigators who will lead such programs. Using a critical leadership theory framework, we conducted a qualitative study of one program to understand how collaborative training and research can support early career investigators in Kenya toward the program transfer goal. ⋯ Mutually beneficial collaborations between Kenyan and US investigators developed during training mitigate these challenges and build a supportive research environment for training. In these collaborations, early career investigators learn how to navigate the complex international research environment to build local HIV research capacity. Shared and mutually beneficial resources within international research collaborations are required to support early career investigators and plans to transfer health research training to African institutions.
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Early seizures (ES) may complicate the clinical course of patients with acute stroke. The aim of this study was to assess the frequency and the predictive factors for early seizures as well the clinical outcome in patients with first-ever stroke. A total of 352 consecutive patients with first-ever stroke, admitted to our department, were included in this retrospective study. ⋯ Early seizures occurred in about 13% of patients with acute stroke. In these patients hemorrhagic transformation is a predictive factor for ES. ES seem to be associated with a worse outcome after acute stroke.
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This corrigendum corrects article "Risks, precipitants and clinical presentation of gastro-oesophageal reflux disease at the Kilimanjaro Christian Medical Centre in Tanzania". Pan Afr Med J. 2014 Oct 1;19:119. doi: 10.11604/pamj.2014.19.119.3575.[This corrects the article DOI: 10.11604/pamj.2014.19.119.3575.].
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Several studies in Sub- Saharan Africa have documented high and increasing premarital sexual activities among adolescents. Younger people face social, peer and cultural pressure to engage in premarital sex. As a result, significant numbers of adolescents are involved in sexual activities at an early age which exposes them to the risk of unintended pregnancy, early marriage, abortion and STIs/HIV/AIDS. This study was conducted to determine Prevalence of premarital sexual practice and associated factors among Health science students of Madawalabu University, Ethiopia. ⋯ Alcohol use, boarding, sex, educational level and discussion about sexuality were significantly associated with premarital sexual intercourses. So, there is the need to step up Reproductive health club at the university to bring behavior change among the students in order to detain the usual consequences of premarital sexual practices and risky sexual behavior.