The Journal of otolaryngology
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Comparative Study
Intrapartum management of severe fetal airway obstruction.
To review our experience with the planned intrapartum management of fetuses with suspected severe airway obstruction. ⋯ Although full cesarean delivery of the fetus significantly reduces fetal-placental circulation times, in comparison with the formal ex utero intrapartum treatment (EXIT) procedure, airway access is improved, maternal complications may be decreased, and high airway procurement success is still safely achieved.
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The objective of this study was to examine whether ciprofloxacin-containing otic drops (Cipro HC Otic Suspension; 0.2% ciprofloxacin, 0.1% hydrocortisone; Alcon, Ontario, Canada) are cochleotoxic in the chinchilla animal model. Five chinchillas in total underwent these studies. Pretreatment distortion-product otoacoustic emissions (DPOAEs) were measured in each ear, followed by a random injection of Cipro to one ear and normal saline to the other. ⋯ No significant change was seen in the ears treated with saline. On SEM examination, the integrity of the stereocilia of the inner and outer hair cells demonstrated no histologic evidence of significant cochlear damage. The finding of reduced DPOAEs suggests a mild local middle ear inflammation caused by the ciprofloxacin or some other component or property of Cipro.
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Cutaneous metastases from laryngeal and hypopharyngeal squamous carcinomas are extremely rare. A high index of clinical suspicion, supplemented with histopathologic evidence, aids in the diagnosis. The prognosis is extremely poor, and treatment is aimed only at palliation of symptoms and improving quality of life.
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Randomized Controlled Trial Clinical Trial
Prevention of nausea and vomiting after middle ear surgery: combination of ondansetron and dexamethasone is the right choice.
To determine the efficacy of a combination of ondansetron and dexamethasone in preventing postoperative nausea and vomiting after middle ear surgery compared with ondansetron alone. ⋯ Prophylaxis with a combination of ondansetron and dexamethasone decreased the incidence of nausea and vomiting after middle ear surgery to a minimum and improved patients' satisfaction significantly in the postoperative period.