Zhonghua fu chan ke za zhi
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Zhonghua Fu Chan Ke Za Zhi · Mar 2007
[Relationship between pain symptoms and clinico-pathological features of pelvic endometriosis].
To study the relationship between pain symptoms and the clinico-pathological features of pelvic endometriosis (EM). ⋯ Pain symptoms including dysmenorrhea, dyspareunia, chronic pelvic pain, and dyschezia are remarkably related to endometriotic nodules at the posterior part of the pelvis or those with deep invasions.
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Zhonghua Fu Chan Ke Za Zhi · Feb 2007
[Effects of nuclear factor-kappaB decoy oligodeoxynucleotide on the function of human umbilical artery smooth muscle cells induced by umbilical sera in preeclampsia].
To study the effects of nuclear factor-kappaB (NF-kappaB) decoy oligodeoxynucleotide (ODN) on the preeclamptic umbilical serum induced expression of precollagen I, III mRNA and tumor necrosis factor-alpha (TNF-alpha) in cultured human umbilical artery smooth muscle cells (HUASMC). ⋯ NF-kappaB cis decoy ODN could down-regulate the proliferation, as well as the expression levels of precollagen and TNF-alpha of HUASMC induced by umbilical serum of preeclampsia. NF-kappaB may play an important role in the pathogenesis of placental artery abnormalities in preeclampsia.
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Zhonghua Fu Chan Ke Za Zhi · Feb 2007
[Polymorphism of catechol-O-methyltransferase gene in relation to the risk of endometrial cancer].
The 4- and 16-hydroxylated metabolites of estrogens have been implicated in carcinogenesis, whereas its 2-hydroxylated metabolites have been shown to have antiangiogenic effects. We aimed to examine whether the polymorphisms of catechol-O-methyltransferase (COMT) involved in the estrogen metabolism are associated with endometrial cancer risk. ⋯ Among the genotypes in women in South China, genotype COMT(Val/Val) is mostly seen, followed by COMT(Val/Met), and COMT(Met/Met) is the least in control group. The endometrial cancer susceptivity of genotype COMT(Val/Val) carriers may be lower than COMT(Met/Met) carriers.
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Zhonghua Fu Chan Ke Za Zhi · Dec 2006
[Value of prenatal diagnosis of placenta previa with placenta increta by transabdominal color Doppler ultrasound].
To assess the value of prenatal diagnosis of placenta previa with placenta increta by transabdominal color Doppler ultrasound. ⋯ Placenta previa is a high-risk factor of placenta increta. Placenta previa increta threatens the lives of the mother and the fetus because of massive hemorrhage. Prenatal color Doppler ultrasound has a high sensitivity and specificity for the identification of placenta previa increta. It has a positive impact on the peripartum clinical management of the affected patients through reducing the death of the mother and the fetus because of unpredictive bleeding while terminating the pregnancy.