South African medical journal = Suid-Afrikaanse tydskrif vir geneeskunde
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To test the practicality, safety and benefits of major cardiothoracic surgery in two rural hospitals. ⋯ The exercise was a resounding success in both measurable and general terms. All operations were successfully performed, with very low adverse outcomes (morbidity, mortality) and good quality of life for all the subjects. The safety and cost-effectiveness of cardiothoracic surgery under primitive conditions were demonstrated. The standard of patient care improved, and local staff acquired good basic skills in patient care. The referral patterns changed for the better and the confidence of the community in the services was enhanced. The risk/benefit ratio of the exercise was commendable. The feasibility of an extended service was encouraging.
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To conduct an audit of the frequency of red cell concentrate transfusions (RCCTs) in infants of different weight categories, the donor exposure rate (DER), in these transfused infants and the volume of blood wasted during each transfusion, and to identify from this baseline information specific categories of infants who would benefit from the introduction of a limited donor exposure programme (LDEP). ⋯ This survey confirmed a high RCCT rate as well as a very high DER in very-low-birth-weight (VLBW) infants treated at a tertiary centre. By assigning a triple or double bag of red cells from one blood donor and extending the storage of blood for small-volume RCCTs in infants from 14 days to 35 days, donor exposure was reduced significantly. We urge the introduction of the multibag blood transfusion system and extended storage period of blood for small-volume RCCT for VLBW infants in South Africa.
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Randomized Controlled Trial Comparative Study Clinical Trial
Hydroxyzine premedication--does it provide better anxiolysis than a placebo?
To determine how effective hydroxyzine is compared with a placebo in providing pre-operative anxiolysis in our hospital population, and to assess the anxiolytic effect of our pre-operative visit. ⋯ Hydroxyzine, in the dose administered and after an appropriate premedication-induction interval, provided no better anxiolysis than a placebo in the pre-operative period. No significant anxiolytic effect was demonstrated by our routine premedication visit.