Acta paediatrica Scandinavica
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Three bilirubin binding tests (hydroxybenzene-azobenzoic acid dye binding method, the estimation of unbound bilirubin by horseradish peroxidase assay and the saturation of albumin by the salicylate saturation index) were performed on pre-exchange samples of blood and repeated 24 hours after the procedure. No significant improvement in bilirubin binding was found even in infants receiving as many as four exchange transfusions. Based on these bilirubin binding tests, we find no evidence that the criteria for subsequent exchange transfusions should be different from the first exchange transfusion.
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1.25-Dihydroxyvitamin D concentrations were measured in 10 preterm infants (mean gestational age 29 weeks, range 26-32; mean birthweight 1226 g, range 980-1700). Total parenteral nutrition was begun after birth and partial enteral feeding was started at 1 week of age. Total enteral feeding was achieved at a mean age of 26 days (range 16-47). ⋯ The mean 1.25-dihydroxyvitamin D concentration +/- SEM was 103.2 +/- 24.0 pmol/l at 1 week (range 9.6-252.0), 141.6 +/- 26.4 at 3 weeks (range 31.2-324.0), 153.6 +/- 21.6 at 6 weeks (range 67.2- 256.8), 165.6 +/- 24.0 at 9 weeks (range 74.4-307.2) and 153.6 +/- 21.6 at 12 weeks (range 76.8-268.8) postnatal age. The mean values at 6, 9 and 12 weeks were significantly higher (p resp. less than 0.01, less than 0.002 and less than 0.005) than in adults (88.8 +/- 7.2; n = 27). 1.25-Dihydroxyvitamin D concentrations were highly variable and did not correlate with 25-hydroxyvitamin D concentrations, plasma calcium and phosphorus concentrations and plasma alkaline phosphatase levels, nor with illness nor postnatal age. The data demonstrate that preterm infants are capable of producing high plasma levels of 1.25-dihydroxyvitamin D.
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Acta Paediatr Scand · May 1985
Evaluation of a transcutaneous oxygen and carbon dioxide monitor in a neonatal intensive care department.
Transcutaneous-PO2 (tc-PO2 (tc-PCO2) at 44 degrees C and transcutaneous-PCO2) at 38, 42, 43 and 44 degrees C were measured with a currently available monitoring system (TCM222, Radiometer, Copenhagen) in 64 newborn infants with severe respiratory insufficiency during the first five days of life. Tc-PCO2 at all four temperatures correlated better with arterial blood-PCO2 (aB-PCO2), than tc-PO2 with aB-PO2. However, the sensitivity and specificity of tc-PO2 and tc-PCO2 were similar with regard to maintaining aB-PO2 and aB-PCO2 within specified limits. ⋯ The coefficient of variation of duplicate measurements was 10% for tc-PO2 and 5% for tc-PCO2. Electrode drift after an average of 3 hours patient monitoring was 2% +/- 6% (1 SD) for tc-PO2 and -3% +/- 6% for tc-PCO2. We conclude that tc-PO2 and tc-PCO2 are a valuable supplement to arterial blood gas measurements, but the variable correlation with arterial blood gas values and the electrode drifts which may occur, mean that they cannot fully replace arterial sampling.
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Acta Paediatr Scand · Jan 1985
Clinical features in hospitalised children with acute gastroenteritis. Does the rotavirus syndrome exist?
In a prospective study of children referred to hospital, rotavirus was identified in 37% of 128 patients with acute gastroenteritis. As compared with patients with non-rotavirus gastroenteritis, those with rotavirus gastroenteritis showed the following clinical characteristics: Age between 5 months and 4 years. Occurrence of the rotavirus infection almost exclusively during the winter season. ⋯ One or more signs of upper respiratory illness were observed in 36% of the patients with rotavirus gastroenteritis and in 35% of those with non-rotavirus gastroenteritis. Consequently, the existence of a rotavirus syndrome is questioned. It is argued that upper respiratory illnesses in patients with rotavirus gastroenteritis could be due to a separate infection occurring coincidentally.
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Acta Paediatr Scand · Nov 1984
Case ReportsA variant of Bartter's syndrome. Bartter's syndrome associated with hydramnios, prematurity, hypercalciuria and nephrocalcinosis.
A case of early onset Bartter's syndrome associated with hydramnios, prematurity, hypercalciuria and nephrocalcinosis is reported. A literature review of Bartter's syndrome supports the hypothesis that the findings in this infant constitute a specific variant of Bartter's syndrome inherited in an autosomal recessive mode. ⋯ This variant of Bartter's syndrome should be included in the differential diagnosis of hydramnios, especially if the woman has had previous hydramnios resulting in a perinatal death. The disorder responds to treatment with indomethacin.