Acta paediatrica Scandinavica
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Acta Paediatr Scand · Nov 1984
Case ReportsSeptic shock and hyperthermia as possible teratogenic factors.
An infant with arthrogryposis and mental retardation is presented. The mother had a septic shock with hyperthermia in the 20th gestational week. The possible relationship between these events is discussed.
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Acta Paediatr Scand · Sep 1984
The silent ductus arteriosus in idiopathic respiratory distress syndrome.
Among 425 pre-term low birthweight babies who survived more than 48 hours there were 130 with idiopathic respiratory distress syndrome, 73 of whom received ventilation for their disease. The ductus arteriosus was considered patent by clinical criteria in 41 of these babies, all but 1 of whom had a murmur. Of the remaining 32 infants there were 2 babies only who died and both were found to have a patent ductus arteriosus which had not been detected clinically. ⋯ The mean age of murmur detection in those ventilated infants considered to have a patent ductus arteriosus was 6 days (range 2-19). Infants without a murmur or other features of a ductus arteriosus did not require to be ventilated beyond day 7 with the exception of the 2 fatalities already mentioned. Thus, relying on clinical criteria and particularly on the presence of a murmur, if sought often, rarely results in missing or seriously delaying the diagnosis of patent ductus arteriosus in babies with severe idiopathic respiratory distress syndrome.
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Acta Paediatr Scand · Mar 1984
Resuscitation of the newborn. Endotracheal administration of epinephrine.
During cardiopulmonary resuscitation, when an intravenous line is not present or easily obtainable, the intracardiac injection of drugs has been a traditional route of choice. However, the intracardiac administration may be associated with serious complications. We have given epinephrine endotracheally to ten newborn infants who all had bradycardia that did not respond to ventilation with 100% oxygen, to heart compression or to bicarbonate infusion. ⋯ All infants had a return to normal heart rhythm within seconds after installation of the epinephrine solution. The establishment of an intravenous line in small infants can be difficult, and the infants are usually intubated before the injection of epinephrine is considered. The endotracheal route should therefore be the first route of choice in the absence of a rapidly obtainable vascular access.
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A one year prospective study of all children under 15 years of age presenting for acute poisoning in Oslo is reported. There were 181 admissions in 179 children, of which 97 (54%) were boys, giving an annual incidence of 2.3%. All children survived without sequelae. ⋯ Seventy-two per cent of all children were admitted within the second hour after the ingestion of the toxic agent. Therapy should therefore be directed towards emptying the stomach with emetics or gastric lavage, unless corrosives or petroleum products are ingested. Childhood poisonings still call for better preventive measures since the toxic agent was found inappropriately stored in 86% of the accidental poisonings.
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Acta Paediatr Scand · May 1983
Serum lipids and lipoproteins in 157 insulin dependent diabetic children and adolescents in relation to metabolic regulation, obesity and genetic hyperlipoproteinemia.
Serum lipids and lipoproteins were measured in 157 insulin dependent diabetic children and adolescents (IDDM) and in 350 healthy reference individuals. Serum triglyceride values were lower and total cholesterol and high density lipoprotein cholesterol higher in IDDM. Metabolic regulation reflected by glucosuria, postprandial blood glucose, number of hypoglycemic episodes and hemoglobin A1c all correlated strongly with serum triglyceride and very low density lipoprotein cholesterol. ⋯ Three children had genetic hyperlipoproteinemia. In IDDM measurement of serum lipids and lipoproteins can thus be used to further assess metabolic regulation. Measurement of serum lipids and lipoproteins seems warranted for future evaluation of the risk of cardiovascular disease in IDDM.