Zhonghua bing li xue za zhi Chinese journal of pathology
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Zhonghua Bing Li Xue Za Zhi · Mar 2008
[Pathologic features of arrhythmogenic right ventricular cardiomyopathy with severe heart failure].
To study the pathologic features of arrhythmogenic right ventricular cardiomyopathy (ARVC) in the phase of heart failure. ⋯ Left ventricular involvement is common in the heart failure phase of ARVC. Extensive interstitial fibrosis, marked hypertrophy and degeneration of myocardial fibers, as well as severe cardiac dilatation with organized thrombi, represent the major pathologic changes which resembles dilated cardiomyopathy.
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Zhonghua Bing Li Xue Za Zhi · Feb 2008
Case Reports[Clinicopathologic study of Churg-Strauss syndrome].
To study the clinical and pathologic features of Churg-Strauss syndrome (CCS). ⋯ Thorough understanding of the clinical and pathologic criteria is essential for arriving at a correct diagnosis of CSS. Although some patients may present with atypical symptoms, lung biopsies often reveal the classic histologic findings which include vasculitis and perivascular allergic granuloma formation.
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Zhonghua Bing Li Xue Za Zhi · Mar 2007
[Activation of CXCR4 in human glioma stem cells promotes tumor angiogenesis].
To isolate, culture and identify glioma stem cells from human malignant glioma cell line U87, and investigate the changes of pro-angiogenic factors production by glioma stem cells followed by activation of CXCR4 and observe their tumorigenesis as well as the expression of vascular endothelial growth factor when implanted into nude mice. ⋯ There are a small fraction of glioma stem cells in human glioblastoma cell line U87. Expressing functional CXCR4 and secreting more pro-angiogenic factors may be involved in tumor angiogenesis mediated by glioma stem cells.