International journal of clinical and experimental medicine
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Post thoracotomy chronic pain is a severe problem that affects the majority of patients and decreases the quality of life. The purpose of this study is to evaluate the long-term effects of thoracal epidural levobupivacaine and intravenous dexketoprofen analgesia formed pre-emptively on the wound site pain after major thoracotomy operations. This randomised, prospective and double-blind study was performed with 60 patients undergoing thoracic surgery. ⋯ When the scores of Patient Satisfaction Scale (PSS) of the cases were compared, they were found to be higher in Group PED as statistically significant during the discharge period (P<0.001). Scores of PSS were higher in Group PED as statistically significant during the postoperative month 6 (P = 0.008). Combined application of pre-emptive intravenous dexketoprofen and thoracal epidural analgesia reduce the chronic post-thoracotomy pain.
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The studies investigating whether transforming growth factor (TGF)-β1-509C/T polymorphism is associated with the risk of ESCC is inconsistent. ⋯ TGF-β1-509C/T polymorphism may contributes to ESCC susceptibility in Chinese population.
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To observe the potency ratio of hyperbaric to isobaric solutions of ropivacaine in subarachnoid block for knee arthroscopy. ⋯ The ED50 of hyperbaric ropivacaine is less than that of isobaric ropivacaine in subarachnoid block anesthesia for knee arthroscopy.
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Current solutions for treating uncontained lumbar disk herniation include laser assisted endoscopic foraminoplasty and Transforaminal Endoscopic Spine System, both of which have some issues in clinical practice. This study aims to report the design of a new instrument for percutaneous posterolateral foraminoplasty. 148 patients with uncontained lumbar disk herniation were treated with percutaneous foraminoplasty followed by transforaminal endoscopic discectomy. Follow up were obtained for 134 cases. ⋯ Follow-up was up to 5 years postoperatively. There were 75 of excellent, 49 of good and 5 of fair according to MacNab score system, with total successful rate up to 92.5%. 5 cases with L5S1 disc herniation complained about irritation to the dorsal root ganglion. In conclusion, the new transforaminal endoscopic discectomy instrument is safe and effective for percutaneous foraminoplasty.
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Propofol is the most widely used drug in the induction of general anesthesia, however its disadvantages of injection pain has always been a problem for clinical anesthetists. Many strategies have been proposed and magnesium sulfate is one of them. This is the first meta-analysis studies evaluating effects of magnesium sulfate pretreatment for preventing propofol-induced injection pain. ⋯ Our meta-analysis suggested that pretreatment with magnesium sulfate intravenously before injecting propofol allow more patients to experiencing no pain during propofol injection and can reduce the intensity of injection pain effectively without causing any adverse effect.