International journal of clinical and experimental medicine
-
The aim of the present study was to explore a novel insight to determine the positive end expiratory pressure (PEEP) for sustained ventilation after lung recruitment in an acute respiratory distress syndrome (ARDS) model. Continuous infusion of oleic acid was performed to establish a ARDS model. Pressure control ventilation (PCV) was applied for lung recruitment with PEEP of 20 cm H2O. ⋯ Static compliance (Cst) and dynamic compliance (Cdyn) were also significantly increased after application of different levels of PEEP ventilation after lung recruitment (P<0.05). There was no significant statistic difference on most hemodynamic parameters (P>0.05) between various levels of PEEP. The application of different PEEP levels around the defined optimal PEEP had an obvious improvement on respiratory mechanics and gas exchange for collapsed lung tissue without influencing the hemodynamics.
-
We evaluated the effects of transcutaneous electric acupoint stimulation (TEAS) on the postoperative quality of recovery after thyroidectomy with general anesthesia in this prospective, randomized, double-blind, placebo-controlled study. ⋯ Preoperative TEAS enhances the quality of recovery, postoperative analgesia and patient's satisfaction, alleviates postoperative side effects and accelerates discharge after general anesthesia for thyroidectomy.
-
Sevoflurane and propofol are widely used in pediatric anesthesia. Neurotoxicity of sevoflurane and propofol in developing brain has been reported and these effects raise concerns on the usage of the drugs. We investigated the influence of rutin, a flavonoid on the neurodegenerative effects of sevoflurane and propofol and on memory and cognition in neonatal rodent model. ⋯ Neuroapoptosis, memory and cognitive deficits observed following anesthetics were comparatively more profound in mice on exposure to combined drug (sevoflurane and propofol) than in those exposed to either of the anesthetics. Rutin at both the doses was effective in reducing the apoptotic cell counts and enhanced the memory and cognitive abilities. Rutin supplementation offered significant protection against anesthetic induced neurodegeneration and learning and memory disturbances.
-
Case Reports
Serious anaphylactic shock induced by hemocoagulase agkistrodon during anesthesia in a 5-year-old child.
We report a case of serious anaphylactic shock in a 5-year-old child undergoing scheduled surgery blank space of a right femoral intramedullary nail removal. The boy had undergone right femoral elastic intramedullary nail fixation surgery 14 months prior, but had no history of allergies. Within 5 minutes of intravenous bonus injection of hemocoagulase agkistrodon (HCA) 1 unit, a widespread transient diffuse erythema was seen on the front of his chest. ⋯ Total amount of dexamethasone sodium phosphate 14 mg was used. To the best of our knowledge, few case reports of HCA-induced anaphylactic shock in children exist. Our report will, therefore, increase awareness of the allergic potential of HCA among pediatric anesthesiologists.
-
The purpose of this study was to compare the study conditions of dental students towards dental education in China and Japan. ⋯ The findings from this study enhance our understanding of study conditions among dental students and help to define strategies to improve student management in both Japan and China.