International journal of clinical and experimental medicine
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The objective of this meta-analysis was to evaluate the efficacy of limited fluid resuscitation during active hemorrhage compared with regular fluid resuscitation and provide strong evidences for the improvement of fluid resuscitation strategies in uncontrolled hemorrhagic shock. ⋯ The results provide convincing evidence that support the continued investigation and use of limited fluid resuscitation during active hemorrhage in the trauma setting.
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Propofol is the most widely used drug in the induction of general anesthesia, however its disadvantages of injection pain has always been a problem for clinical anesthetists. Many strategies have been proposed and magnesium sulfate is one of them. This is the first meta-analysis studies evaluating effects of magnesium sulfate pretreatment for preventing propofol-induced injection pain. ⋯ Our meta-analysis suggested that pretreatment with magnesium sulfate intravenously before injecting propofol allow more patients to experiencing no pain during propofol injection and can reduce the intensity of injection pain effectively without causing any adverse effect.
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To evaluate the value of conventional ultrasound and contrast-enhanced ultrasound (CEUS) in determining the severity of active Crohn's disease. ⋯ Both conventional ultrasound and CEUS are reliable methods in determining the severity of active Crohn's disease. The diagnostic performance in terms of Youden's index was highest for the Imax of the interior layer, in comparison with all other features on conventional ultrasound, qualitative CEUS, and quantitative CEUS.
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There are many risk factors for the cause of postoperative cognitive dysfunction (POCD), however, the anesthesia selection always trigger controversy for the POCD occurrence. This study aims to explore the relationship between the anesthesia and the occurrence of POCD in elder patients, and also investigate the mechanism of the POCD. One hundred elder patients with hip replacement were included in this study, which were divided into general anesthesia (GA) and epidural analgesia (EA) group. ⋯ MMSE scores of POCD patients positively correlated with Aβ or tau level (P < 0.05). In conclusion, the epidural analgesia method was better than general analgesia method for the hip replacement in elder patients. The mechanism of the POCD may be caused by the enhancement of Aβ and Tau protein.
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To study the effects of dexmedetomidine (Dex) on cellular immunity during the perioperative period in children with brain neoplasms. ⋯ Dex given by a continuous intravenous infusion during general anesthesia may effectively inhibit the stress responses and reduce the inhibition of cellular immunity in children with brain neoplasms during the perioperative period.