Nan fang yi ke da xue xue bao = Journal of Southern Medical University
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Nan Fang Yi Ke Da Xue Xue Bao · Jul 2007
[Effects of serum of rats with ventilator-induced lung injury on endothelial cell permeability and its mechanism].
To investigate the effects of inflammatory mediators in the serum of rats with ventilator-induced lung injury (VILI) on endothelial cellular cytoskeleton and monolayer cellular permeability and explore the molecular mechanism of VILI-induced lung edema. ⋯ The pro-inflammatory mediators in the serum of rats with high tidal volume ventilation increases endothelial cell permeability by reorganizing actin cytoskeleton, and pretreatment with ulinastatin can lessen the hyperpermeability by inhibiting multiple pro-inflammatory mediators.
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Nan Fang Yi Ke Da Xue Xue Bao · May 2007
Randomized Controlled Trial[Phase IIa clinical trail of hemocoagulase acutus for injection].
To evaluate the efficacy and safety of hemocoagulase acutus for injection and determine its curative dose. ⋯ Hemocoagulase acutus for injection has good hemostatic effect for controlling capillary hemorrhage at the abdominal incisions and can be safely used in the surgical patients.
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Nan Fang Yi Ke Da Xue Xue Bao · May 2007
Randomized Controlled Trial[Time window for intubation after rocuronium administration during target-controlled infusion of propofol and sulfentanil].
To define the ideal time window for intubation after rocuronium administration during target-controlled infusion (TCI) ofpropofol and sulfentanil. ⋯ The condition of vocal cord can be more suitable for intubation at 2-4 min than at 1 min after rocuronium administration as the ideal time window for intubation during TCI of propofol and sulfentanil.
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Nan Fang Yi Ke Da Xue Xue Bao · May 2007
[Developmental changes in synaptic and extrasynaptic N-methyl-D-aspartate receptors in cultured rat hippocampal neurons].
To investigate changes in synaptic and extrasynaptic N-methyl-D-aspartate receptors (NMDAR) during the development of cultured rat hippocampal neurons. ⋯ There can be developmental changes in synaptic and extrasynaptic NMDAR channel currents in cultured rat hippocampal neurons, indicating that different NMDAR subtypes are expressed in the synaptic and extrasynaptic regions during the development of the hippocampal neurons. In 1-week neurons, NR2B are predominant both in synaptic and extrasynaptic regions, and at 2 weeks, synaptic NR2B are replaced by NR2A but NR2B still remains the predominant subtypes outside the synapses.
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Nan Fang Yi Ke Da Xue Xue Bao · Mar 2007
Randomized Controlled Trial[Percutaneous intradiscal oxygen-ozone injection for lumbar disc herniation: no need of perioperative antibiotic prophylaxis].
To evaluate the feasibility of no antibiotic administration to prevent infection during the perioperative period of percutaneous intradiscal ozone-injection for treatment of lumbar disc herniation. ⋯ Prophylaxis antibiotics is not necessary during the perioperative period of percutaneous intradiscal ozone injection for lumbar disc herniation.