Klinicheskaia meditsina
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Klinicheskaia meditsina · Jan 2000
Comparative Study[Josamycin combination with ranitidine in therapy of gastroduodenal ulcer: clinical efficiency].
Efficacy of a novel eradication treatment with ranitidine, trichopol and jozamycin was compared to that of the standard three-component therapy and monotherapy with ranitidine in 76 patients with exacerbation of gastric and duodenal ulcer. Therapeutic monitoring of ranitidine was performed. In relation to healing of ulcer defect and eradication of Helicobacter pylori, jozamycin is not less effective and more safe than standard three-component therapy. Interaction of the scheme components increases plasma concentration of ranitidine especially in patients with concomitant hepatic and renal diseases.
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Klinicheskaia meditsina · Jan 2000
[Differential diagnosis of hemotamponade in myocardial infarction and aortic dissecting aneurysm].
Clinical picture was analysed for 29 patients with myocardial infarction and 12 patients with dissecting aortic aneurysm who had died of cardiac hemotamponade. Similar symptoms of these conditions did not allow to establish pathognomonic clinical criteria. To prevent diagnostic mistakes, it is recommended to use early device examinations.
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Klinicheskaia meditsina · Jan 2000
[The role of renin-angiotensin system in pathogenesis of pulmonary hypertension in patients with chronic obstructive pulmonary disease].
Renin-angiotensin system (RAS) and hemodynamics in pulmonary artery (PA) were assessed in 25 patients with chronic non-obstructive bronchitis and 73 patients with chronic obstructive pulmonary diseases (COPD). RAS in COPD patients was activated. ⋯ The data were obtained on the essential role of RAS in the onset and progression of pulmonary hypertension. This allows to design new approaches to pathogenetic treatment of secondary pulmonary hypertension.