Harefuah
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Off-label use of drugs is common in all areas of medicine, but is specifically prevalent in pediatrics, oncology and in treating rare diseases. Such use may benefit patients, but on the other hand, there is concern about the safety aspects of these treatments. Besides the legal, ethical and safety issues associated with off-label use, arises the issue of whether such prescribing should be reimbursed by public funds. ⋯ Occasionally, health plans agreed to subsidize critically needed off-label treatments, although they did not receive public funding for off-label indications. In this article we review the problems associated with off-label prescribing, the reasons why the MoH changed its policy at the beginning of 2009 to permit, in very special circumstances, reimbursement of off-label treatment. We also provide a brief summary of off-label policies in a few western countries.
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The sexual and reproductive behaviors of Ethiopians immigrating to Israel have changed drastically as they transition to a new culture. With the postponement of age of marriage and an increase in sexual activity prior to marriage, there is an increased risk of unplanned pregnancy among young people in this group. The increasing rates of unplanned pregnancy among immigrants in developed countries have become a formidable public health challenge. ⋯ Israeli women of Ethiopian origin have a considerably higher risk of requesting an abortion than other Israeli women of the same age. Although women of Ethiopian origin born in Israel had a lower rate of requests for abortions compared to those born in Ethiopia, this rate is still higher in comparison to other Israelis. Females born in Ethiopia have even higher rates. It is evident that these youth need exposure to appropriate preventive interventions and that this group cannot be considered homogenous. We recommend that appropriate interventions should be based on the specific needs of sub-groups within them and on appropriate analytical and development research.