Monaldi archives for chest disease = Archivio Monaldi per le malattie del torace / Fondazione clinica del lavoro, IRCCS [and] Istituto di clinica tisiologica e malattie apparato respiratorio, Università di Napoli, Secondo ateneo
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Monaldi Arch Chest Dis · Jan 1993
ReviewTrends in therapy of abnormal airway epithelial ion and liquid transport.
Airway epithelial ion transport, particularly that of sodium and chloride, influences the volume and composition of airway surface liquid. Defects in ion transport play an important role in the pathogenesis of some chronic airway diseases, for example cystic fibrosis. New aerosolised therapies that modulate defects in ion transport, and hence influence the natural history of cystic fibrosis are currently undergoing scrutiny. Agents such as sodium channel inhibitors and chloride channel activators are included in this class.
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Monaldi Arch Chest Dis · Jan 1993
Considerations on 200 cases of percutaneous cricothyroidotomy (minitracheotomy).
More than 10 yrs ago, minitracheotomy was suggested as an elective method in the treatment of sputum retention, resulting from impaired ability to cough, in many medical and surgical diseases. We report our experience of 200 cases of percutaneous cricothyroidotomy in our Intensive Care Unit (145 patients), and in other wards (55 patients). ⋯ About 60-70% of treated patients benefited by minitracheotomy and did not require more invasive interventions. A better control of technique, moreover, allowed other possible applications to be discovered.